STEP 1- RNA viruses

Question 1

These are the two mneumonics to help remember the RNA viruses:

1. “i went to a RETRO TOGA party and drank FLAVORED CORONA and ate HIPPY CALIFORNIA PICKLES”
   * *Those are the ____ sense RNA viruses
2. “Always Bring Polymerase Or Fail Replication”
   * *Those are the _____ sense RNA viruses
3. There are two viruses not included in those mneumonics (you be DR!!)

Answer 1

1. Retroviruses, Togaviruses, flaviviruses, coronaviruses, hepevirus, caliciviruses, picornaviruses
   * *These are the positive sense RNA viruses
2. Arenaviruses, Bunyaviruses, Paramyxoviruses, Orthomyxoviruses, Filoviruses, Rhabdoviruses
   * *These are the negative sense RNA viruses
3. The two RNA viruses not included in those are the Reovirus and Delta virus…more on that later

Question 2

Which RNA viruses are naked? Which are enveloped?

“always give CPR and a PAPP to naked Hippys”

Answer 2

Naked:
C-Caliciviruses
P-Picornavirus
R-Reovirus
Hippy- Hepevirus

Enveloped: all others

Question 3

Which viruses have an icosahedral capsid? Which have a helical capsid?

Answer 3

Thankfully, all the positive sense viruses have an icosahedral capsid. All the negative sense viruses have a helical capsid

Question 4

Medical importance of Reoviruses (2)

What do each cause

Answer 4

1. Coltivirus–Colorado tick fever

2. Rotavirus– severe diarrhea in children

Question 5

Medical importance of Picornaviruses (4)

“I went for a PEEK on the PERCH”

Answer 5

P-Polivirus
E-Echovirus: aseptic meningitis 
R- Rhinovirus: cold
C-Coxsackievirus
H- Hepatitis A--> acute viral hepatitis

Question 6

Coxsackieviruses cause (5)

Answer 6

1. Aseptic meningitis
2. Herpangina (mouth blisters and fever)
3. Hand, foot, and mouth disease
4. myocarditis
5. pericarditis

Question 7

Medical importance of Hepevirus (1)

Answer 7

1. Hepatitis E

Question 8

Medical importance of Calicivirus (1)

Answer 8

1. Norovirus

Question 9

Medical importance of Flaviviruses (5)

1 major one, two important, two not so much

Answer 9

1. Hepatitis C
2. Yellow fever
3. Dengue fever
4. West Nile Virus
5. St. Louis encephalitis

Question 10

Medical importance of Togavirus (3)

*One really important one

Answer 10

1. Rubella
2. Eastern equine encephalitis
3. Western equine encephalitis

Question 11

Medical importance of Retroviruses (2)

Answer 11

1. HTLV– T cell leukemia

2. HIV/AIDS

Question 12

Medical importance of Coronaviruses (2)

Answer 12

1. Common cold

2. SARS

Question 13

Medical importance of Orthomyxoviruses- 1

Answer 13

1. Influenza virus

Question 14

Medical importance of PaRaMyxovirus- 4

Answer 14

1. Parainfluenza– croup
2. RSV–bronchiolitis
3. Measles and Mumps

Question 15

Medical importance of Rhabdovirus-1

Answer 15

Rabies

Question 16

Medical importance of Filoviruses-1

Answer 16

Ebola

Question 17

Medical importance of Arenaviruses- 2

Answer 17

1. LCMV (lymphocytic choriomeningitis virus)

2. Lassa fever

Question 18

Medical importance of Bunyaviruses- 4 (good luck with these poof)

Answer 18

1. California encephalitis
2. Sandfly-Rift Valley fever
3. Crimean-Congo hemorrhagic fever
4. Hantavirus

Question 19

Medical importance of Deltavirus

Answer 19

1. Hepatitis D–defective virus that requires HBV co-infection