Spleen Biopsy Interpretation Flashcards
1
Q
Categories of spleen pathology
A
White pulp - reactive: ex, follicular hyperplasia
White pulp - malignant: ex, hepatosplenic T cell lymphoma
Red pulp - congestion: ex, congenital hemolytic anemia
Red pulp - infection: ex, infectious mononucleosis
Red pulp - histiocytic proliferation: ex, histiocytic and DC neoplasms
Red pulp - extramedullar hematopoiesis: ex, leukemia/MDS/MPN
Red pulp - nonhematopoietic tumors: ex, cysts, hamartomas
2
Q
Splenic follicular hyperplasia
A
May be focal or diffuse. Occurs secondarily in infectious or immunologic processes (ITP, hemolytic anemia, RA).
