Spironolactone Flashcards
1
Q
How does spironolactone work?
A
Potassium-sparing diuretic - steroid medication that promotes the excretion of Na by inhibiting aldosterone
(also has anti-androgenic properties)
2
Q
What are the indications for spironolactone?
A
Oedema, ascites in liver cirrhosis, nephrotic syndrome, resistant hypertension, hyperaldosteronism, hirtuism and acne
3
Q
What are the contraindications of spironolactone?
A
Addison’s disease, anuria, hyperkalaemia
4
Q
Name a drug inteaction of spironolactone
A
Digoxin
5
Q
What are the side effects of spironolactone?
A
Urinary frequency, dehyration, hyperkalaemia, hyponatraemia, hypotension, acidosis
