Simvastatin Flashcards

1
Q

How does simvastatin work?

A

Reduces cholesterol formation

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2
Q

What are the indications of simvastatin?

A

Primary hypercholesterolaemia, prevention of cardiovascular events in patients with atherosclerotic cardiovascular disease/T2DM

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3
Q

What are the contraindications of simvastatin?

A

High alcohol intake, liver disease, pregnancy/breastfeeding

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4
Q

What are the drug interactions of simvastatin?

A

Use a lower dose in those taking: amiodarone, ciclosporin, erythromycin

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5
Q

What are the side effects of simvastatin?

A

Constipation/diarrhoea, dizziness, asthenia, thrombocytopenia

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