Amiodarone Flashcards
1
Q
How does amiodarone work?
A
Antiarrhythmic - slows the conduction rate and prolongs the refractory period of AV and SAN
2
Q
What are the indications of amiodarone?
A
Atrial/ventricular fibrillation, Wolff-Parkinson-White syndrome, ventricular tachycardia
3
Q
What are the contraindications of amiodarone?
A
Severe conduction disturbances, thyroid dysfunction, acute porphyrias,
Not for pregnancy/breastfeeding
4
Q
NAme some drug interactions of amiodarone
A
Potentiates warfarin so patients need wafarin dose altering, inhibits CYP450 so reduces clearance of: cyclosporin, digoxin, flecadine
5
Q
Name some side effects of amiodarone
A
Arrhythmias, nausea, hyperthyroidism (Contains similar ingredient to thyroxine), hepatic disorders, respiratory disorders
