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Y3 Drugs | Cardiovascular > Digoxin > Flashcards

Digoxin Flashcards

1
Q

How does digoxin work?

A

Inhibits the Na+/K+/ATPase in the myocardium. Causes an increase in intracellular Ca which increases heart contractility, consequently decreasing the heart rate

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2
Q

What are the indications of digoxin?

A

AF, atrial flutter, heart failure

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3
Q

What are the contraindications for digoxin?

A

Constrictive pericarditis, cardiomyopathy, heart block, Woldd-Parkinson-White syndrome, ventricular fibrillation/tachycardia

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4
Q

What are the drug interactions of digoxin?

A

Amiodarone, verapamil, quinidine : all increase concentration of digoxin

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5
Q

What are the side effects of digoxin?

A

Dizziness/diarrhoea/nausea/vomiting, arrhythmias, cardiac conduction disorder

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Y3 Drugs | Cardiovascular (17 decks)

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