Furosemide Flashcards

1
Q

How does furosemide work?

A

Loop diuretic - acts on the thick ascending loop of Henle
Overall effect is to cause water (and Na, K, Cl) to remain in filtrate at ascending loop, which is excreted as urine (does this by blocking cotransporter)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the indications of furosemide?

A

Reduces the amount of water in the body so is useful for:

  • congestive heart failure
  • oedema
  • resistant hypertension
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the contraindications of furosemide?

A

Anuria, hyponatraemia/kalaemia, renal failure, dehydration/hypovolaemia, can also exacerbate gout (by increasing the concentration of uric acid in blood through water loss)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Name a drug interaction with furosemide

A

Aspirin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are some side effects of furosemide?

A

Dizziness/headache/fatigue, orthostatic hypotension, electrolyte imbalance, nausea, metabolic alkalosis,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Name this drug: acts on ascending loop of Henle to cause Na, K, Cl to remain in filtrate, causing water to leave blood through osmosis and out of filtrate into urine

A

Loop diuretic (furosemide)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly