Spirochetes and Miscellaneous Bacteria Flashcards
Helically coiled bacteria transmitted through arthropod bites (e.g. lice, ticks)
Borrelia spp.
Borrelia spp. are ________ bacteria transmitted through arthropod bites (e.g. lice, ticks).
Helically coiled
How are Borrelia spp. transmitted?
Through arthropod bites (e.g. lice, ticks)
These are flexible organisms resembling a stretched spiral
Borrelia spp.
Borrelia spp. are flexible organisms resembling a _______.
Stretched Spiral
________ is the causative agent of Louse-Borne Relapsing Fever.
Borrelia recurrentis
Borrelia recurrentis is the causative agent of _____.
Louse-Borne Relapsing Fever
Vector of Louse-Borne Relapsing Fever
Human louse (pediculus humanus)
The scientific name of human louse is _____.
Pediculus humanus
Symptoms of Louse-Borne Relapsing Fever
High fever, muscle and bone pain, confusion
________ is the causative agent of Tick-Borne Relapsing Fever.
Borrelia hermsii or Borrelia parkeri
Borrelia hermsii or Borrelia parkeri is the causative agent of _______.
Tick-Borne Relapsing Fever
Vector of Tick-Borne Relapsing Fever
Ornithodoras ticks
________ is the causative agent of Lyme Disease.
Borrelia burgdorferi
Borrelia burgdorferi is the causative agent of ________.
Lyme Disease
Vector of Lyme Disease
Ixoda Ticks and Deer Ticks
Lyme Disease has how many stages?
3
Stage 1 of Lyme Disease
Presence of erythema chronicum migrans (lesion; bull’s eye rashes)
Erythema chronicum migrans resemble _______.
bull’s eye
Which Stage of Lyme Disease?
Appearance of lesion; Erythema chronicum migrans (bull’s eye rashes)
Stage 1
Stage 2 of Lyme Disease
Dissemination through blood, bones, CNS, heart, and liver
Which Stage of Lyme Disease?
Dissemination through blood, bones, CNS, heart, and liver
Stage 2
Stage 3 of Lyme Disease
Neurological abnormalities, arthritis and skin lesion (chronic stage)
Which Stage of Lyme Disease?
Neurological abnormalities, arthritis and skin lesion (chronic stage)
Stage 3
Culture for Borrelia spp.
- Kelly’s medium
- Barbour-Stoenner Kelly’s (BSK)
Borrelia spp. can also be detected through ________.
Serological tests
Serological test for Borrelia spp.
- ELISA
- Western Blot
Golden standard for the serological identification of Borrelia spp.
Western Blot
A serological test used to identify the DNA
Western Blot
A serological test used to identify the RNA
Northern Blot
Western blot is used for the identification of _____.
DNA
Northern blot is used for the identification of _____.
RNA
Tightly twisted organisms resembling a cork screw
Treponema spp.
Treponema spp. are tightly twisted organisms resembling a ______.
Cork Screw
________ is the causative agent of Venereal Syphilis
Treponema pallidum subsp. pallidum
Treponema pallidum subsp. pallidum is the causative agent of _______.
Venereal Syphilis
Other terms for Venereal Syphilis
- Great pox
- Evil pox
- French/Italian pox
- Spanish disease
Mode of transmission for Venereal Syphilis
- Sexual
- Direct
- Transplacental
Syphilis in newborns is called _____.
Congenital Syphilis
____ is seen once the baby is born.
Congenital Syphilis
What are the manifestations seen in Congenital Syphilis?
Hutchinsonian Triad
* Notched teeth
* Keratitis
* Eczema
What do you call the group of manifestations seen in Congenital Syphilis?
Hutchinsonian Triad
Venereal Syphilis has how many stages?
4
Stages of Venereal Syphilis
- Primary syphilis
- Secondary syphilis
- Latent syphilis
- Tertiary syphilis
Primary syphilis
Presence of hard chancre (painless and firm)
Which Stage of Venereal Syphilis?
Presence of hard chancre that is painless and firm
Primary syphilis
Secondary syphilis
Condylomata lata (wart-like lesions)
Which Stage of Venereal Syphilis?
Presence of wart-like lesions called Condylomata lata
Secondary syphilis
Wart-like lesions seen in syphilis is called ______.
Condylomata lata
Latent syphilis
Absence of clinical symptoms
Which Stage of Venereal Syphilis?
Absence of clinical symptoms
Latent syphilis
Tertiary syphilis
Presence of gummas, neurosyphilis
Which Stage of Venereal Syphilis?
Presence of gummas, neurosyphilis
Tertiary syphilis
What kind of microscope is used in observing Treponema pallidum subsp. pallidum during Direct Microscopic Examination?
Darkfield Microscope
________ can be used to identify Treponema pallidum subsp. pallidum
Serological tests
Heavy metals used for treating Treponema pallidum subsp. pallidum
Arsenic, Arsphenamine, Salvarsan
Drug of Choice for Treponema pallidum subsp. pallidum
Penicillin
A reaction wherein large quantities of toxins are released as the bacterium dies during treatment.
Jorisch-Herxheimer Reaction
Which bacterium is associated with Jorisch-Herxheimer reaction?
Treponema pallidum subsp. pallidum
________ is the causative agent of Yaws
Treponema pallidum subsp. pertenue
Treponema pallidum subsp. pertenue is the causative agent of ________.
Yaws
A chronic non-venereal disease of skin and bones
Yaws
Mode of transmission for Yaws
Direct contact of traumatized skin with infected lesion
________ causes non-venereal syphilis and endemic syphilis
Treponema pallidum subsp. endecume
Treponema pallidum subsp. endecume causes _____.
Non-venereal syphilis and Endemic syphilis
________ is the causative agent of Bejel
Treponema pallidum subsp. endecume
Treponema pallidum subsp. endecume is the causative agent of _____.
Bejel
Mode of transmission for Bejel
Mouth to mouth by utensils
A lesion in the oral cavity, oral mucosa, skin, bones and nasopharynx
Bejel
________ is the causative agent of Pinta
Treponema carateum
Treponema carateum is the causative agent of _____.
Pinta
An ulcerative skin disease
Pinta
Mode of transmission for Pinta
Direct contact of traumatized skin with infected tissue
Tightly twisted organisms with one or both ends bent into a hook
Leptospira spp.
A non-pathogenic species of Leptospira that is found in water and soil
Leptospira biflexa
________ is the causative agent of Leptospirosis
Leptospira interrogans
Leptospira interrogans is the causative agent of _____.
Leptospirosis
Leptospirosis is a ______ infection.
zoonotic
Mode of transmission for Leptospirosis
Direct contact with urine of animals
____ is the severe form of Leptospirosis.
Weil’s Disease
Weil’s disease is associated with ______.
Leptospira interrogans serovar. icterohemorrhagiae
Leptospira interrogans serovar. icterohemorrhagiae is associated with _____.
Weil’s Disease