Spirochetes Flashcards
Diagnosis of Leptospirosis in dogs
Microscopic Agglutination Test
Papillomatous Digital Dermatitis (PPD)
Grosing cause of lameness of cows in the US dairy industry
Decreased milk production
Lower reproductive efficiency
Disease
Etiologic Agent
Rabbit Syphilis - Vent Disease
Treponema paraluis- cuniculi
Most common leptospira serovars that cause equine leptospirosis
Serovars pomona and grippotyphosa
Clinical signs of Leptospirosis in dogs
Mild or no signs
Acute febrile illness
Renal or hepatic injury, uveitis, pulmonary hemorrhage, abortion
PU/PD, dehydration, vomiting, diarrhea, inappetence, lethargy, abdominal pain
Hepatic and renal Failure
Bleeding abnormalities and DIC
Pathogenic Leptospira species are maintained in
Renal tubules of reservoir animals
Disease
Possible etiologic agent
Papillomatous Digital Dermatitis - PDD
Borrelia is trasmitted via
arthropod vector
Virulence of Borrelia is associated with
Antigenic variation in major outer surface lipoproteins (OPS)
Causative agent of Papillomatoius Digital Dermatitis (PPD) - Hairy Heel Warts (HHW)
Treponema pallidum
Pathogenesis of Lyme Disease
- Tick becomes infected when feeding on bacteremic animal
- Tick ingests blood, spirochete up regulates expression of outer surface protein
- Spirochete moves from midgut to hemolymph to salivary gland
- Transmitted to animal when tick feeds
Treponema pallidum infection in humans
Syphilis
Transmission of Bracyspira
Asymptomatic carrier pigs are the most important mode of transmission
Diagnosis of Brachyspira infection
Direct staining - Wrights Giemsa, Victoria Blue
Causative agent of Swine Dysentery
Brachyspira hyodysenteriae
Clinical signs of Brachyspira infection
Bloody diarrhea, dehydration, weight loss
Grey to strawberry colored feces and dehydration
Brachyspira
Gram Negative
Strong beta-hemolytic
Oxygen tolerant
Anaerobic
Loosly coiled, motile spirochete
Diagnosis of Leptospirosis in cattle and ruminants
Urine FA and PCR
Rabbit Syphilis - Vent Disease
Self limiting disease
Perineal and Facial lesions
Increase susceptibility to other infection
Epidermal hyperplasia with erosion and ulcers