Spirochetes Flashcards

1
Q

Diagnosis of Leptospirosis in dogs

A

Microscopic Agglutination Test

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2
Q

Papillomatous Digital Dermatitis (PPD)

A

Grosing cause of lameness of cows in the US dairy industry

Decreased milk production

Lower reproductive efficiency

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3
Q

Disease

Etiologic Agent

A

Rabbit Syphilis - Vent Disease

Treponema paraluis- cuniculi

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4
Q

Most common leptospira serovars that cause equine leptospirosis

A

Serovars pomona and grippotyphosa

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5
Q

Clinical signs of Leptospirosis in dogs

A

Mild or no signs

Acute febrile illness

Renal or hepatic injury, uveitis, pulmonary hemorrhage, abortion

PU/PD, dehydration, vomiting, diarrhea, inappetence, lethargy, abdominal pain

Hepatic and renal Failure

Bleeding abnormalities and DIC

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6
Q

Pathogenic Leptospira species are maintained in

A

Renal tubules of reservoir animals

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7
Q

Disease

Possible etiologic agent

A

Papillomatous Digital Dermatitis - PDD

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8
Q

Borrelia is trasmitted via

A

arthropod vector

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9
Q

Virulence of Borrelia is associated with

A

Antigenic variation in major outer surface lipoproteins (OPS)

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10
Q

Causative agent of Papillomatoius Digital Dermatitis (PPD) - Hairy Heel Warts (HHW)

A

Treponema pallidum

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11
Q

Pathogenesis of Lyme Disease

A
  • Tick becomes infected when feeding on bacteremic animal
  • Tick ingests blood, spirochete up regulates expression of outer surface protein
  • Spirochete moves from midgut to hemolymph to salivary gland
  • Transmitted to animal when tick feeds
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12
Q

Treponema pallidum infection in humans

A

Syphilis

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13
Q

Transmission of Bracyspira

A

Asymptomatic carrier pigs are the most important mode of transmission

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14
Q

Diagnosis of Brachyspira infection

A

Direct staining - Wrights Giemsa, Victoria Blue

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15
Q

Causative agent of Swine Dysentery

A

Brachyspira hyodysenteriae

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16
Q

Clinical signs of Brachyspira infection

A

Bloody diarrhea, dehydration, weight loss

Grey to strawberry colored feces and dehydration

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17
Q

Brachyspira

A

Gram Negative

Strong beta-hemolytic

Oxygen tolerant

Anaerobic

Loosly coiled, motile spirochete

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18
Q

Diagnosis of Leptospirosis in cattle and ruminants

A

Urine FA and PCR

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19
Q

Rabbit Syphilis - Vent Disease

A

Self limiting disease

Perineal and Facial lesions

Increase susceptibility to other infection

Epidermal hyperplasia with erosion and ulcers

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20
Q

Treatment for Tremponema pallidum in cattle

A

Spray feet with antibiotic solutions while they are in milkin parlor

21
Q

Most common vector borne bacterial disease in humans

A

Lyme Disease

22
Q

Arthropod vector of Lyme Disease

A

Ixodes scapularis

Ixodes pacificus

23
Q

Diagnosis of Rabbit Syphilis

A

Demonstration of spirochetes in typical lesions

24
Q

Leptospirosis in swine is charcterized by

A

Reproductive failure as evidence by infertility and sporadic abortion

25
Q

Treatment of Leptospirosis in cattle and ruminants

A

Vaccination and Antibiotics

26
Q

Clinical signs of Canine Lyme Disease

A

Fever, acute arthritis, athralgia and lameness

Infection usually subclinical

27
Q

Species of leptospira host adapted in cattle resulting in reproductive failure due to early embryonic death and repeated bleeding

A

Leptospira borgpetersenni serovar hardjo

28
Q

Brachyspira hyodysenteriae is chemotactically attracted to

A

Hog Mucin

29
Q

Clinical leptospirosis in horses is most commonly associated with

A

Abortions and systemic illness in foals

30
Q

Lesions found in large intestines only

Sharp line of demarcation at ileocecal junction

Fibronecrotic pseudomembranous colitis with granular, hyperemic mucosa - Advanced cases

A

Brachyspira pilosicoli

31
Q

Pathogenesis of Leptospira infection

A
  • Penetrates epithelial barriers
  • Bacteremia
  • Enter liver, kidney, spleen, CNS, genital tract
  • Antibodies develop
  • Shedding
32
Q

Causative agent of Avian Borrelosis

A

Borrelia anserina

33
Q

Causative agent of Relapsing Fever Borreliae

A

Borrelia recurrentis

34
Q

Reservoir animals excrete Leptospira through

A

Urine

35
Q

Bracyspira pilosicoli

A

Causes intestinal spirochetosis in animals and humans

36
Q

Swine Dysentery affects pigs of what age

A

Actively growing pigs 6-12 weeks old

37
Q

Location of flagella in Spirochetes

A

Periplasmic space

38
Q

Lesions assoicated with Brachyspira infection

A

Sharp line of demarcation at ileocecal junction, fibronecrotic pseudomembranous colitis with granular, hyperemic mucosa

39
Q

Treatment for Canine Lyme Disease

A

Doxycycline

40
Q

Clinical signs of leptospriosis in foals

A

Hemolysis and vasculitis with petechial hemorrhage, hemoglobinuria, anemia, icterus, conjunctival suffusion

41
Q

Leptospira serovars responsible for swine leptospirosis

A

Serovar pomona and bratislava

42
Q

Causative agent of Rabbit Syphilus - Vent Disease

A

Treponema paraluis-cuniculi

43
Q
A

Borrelia

44
Q
A

Treponema

45
Q

Treatment for Leptospirosis in dogs

A

Supportive care and antibiotics

46
Q

Clinical signs of Leptospirosis in cattle and ruminants

A

High fever, hemolytic anemia, hemoglobinuria, jaundice, pulmonary congestion, meningitis

47
Q

Diagnosis of Canine Lyme Disease

A

SNAP Test

Western blot

48
Q

Causative agent of Lyme Disease

A

Borrelia burgdorferi

49
Q

Leptospira serovar pomona is endemic in was species

A

California Sea Lion