spirochaetes Flashcards

1
Q

What is the feature of spirochaetes ?

A

large group of spiral motile Gram negative bacteria

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2
Q

mainly by sex, direct contact with lesions, blood transfusion

A

acquired Syphilis

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3
Q

Transplacental, (from mother to fetus)

A

congenital syphilis

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4
Q

Primary Syphilis:

A

highly infectious
Chancre: local, painless
Regional lymphadenopathy

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5
Q

Secondary Syphilis:

A

highly infectiuos

macular rash or warty lesions, condylomas

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6
Q

Tertiary Syphilis is characterized by ?

A

gummas (chronic granulomas)

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7
Q

What is the test of Syphilis Treponemas pallidum ?

A

Flocculation tests (VDRL test , Rapid Plasma Reagin (RPR) test)

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8
Q

What is the Treatment of Treponema pallidum ( Syphilis )

A

Benzathine penicillin

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9
Q

Treponema pallidum subspecies pertenue→ Yaws leads to ?

A

goundou , gangosa

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10
Q

proliferative exostoses of nose bone ?

A

goundou

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11
Q

particularly around nose ?

A

gangosa

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12
Q

depigmented, resembling vitiligo ?

A

Pinta

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13
Q

What is the vector and reservoir of Epidemic RF ?

A

Vector is Lice

reservoir) is human

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14
Q

Endemic RF:

A

Vector is Ticks

reservoir) is Rodents

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15
Q

The The relapses of Borrelia causing Relapsing Fever

are due ?

A

antigenic variations.

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16
Q

Specimen blood during febrile attack in ?

A

Borrelia causing Relapsing Fever

17
Q

What is the stain of Borrelia causing Relapsing Fever ?

A

Giemsa’s stain: shows large spirochetes diagnosis

18
Q

Borrelia vincentii ?

A

commensal in the mouth in few numbers.

19
Q

Vincent’s angina is ?

A

mouth ulcers on the tonsils and the gum

20
Q

Septicemic (acute) phase of Leptospira cause ?

A

fever, headache, conjunctival suffusion.

21
Q

Delayed phase of Leptospira cause ?

A

aseptic meningitis.

22
Q

Icteric leptospirosis(Weil’s disease) of Leptospira leads to ?

A

multiorgan dysfunction

23
Q

Treatment of Leptospira ?

A

Penicillin G

24
Q

What is the feature of ACTINOMYCETES ?

A

Gram-positive branching bacilli , anaerobic

25
Q

multiple abscesses drained by sinuses→ pus containing sulfur granules is ?

A

Actinomyces israelii

26
Q
A

Nocardia (weakly acid fast.)

27
Q
A
28
Q

Broncho-pulmonary infection → by ?

A

N. asteroids

29
Q

Cutaneous nocardiasis (Actinomycetoma) → by?

A

N. brasiliensis.

30
Q

What is the feature of Nocardia ?

A

Gram-positive branching bacilli

Modified Ziehl Neelsen: branching acid-fast bacilli