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Micro 🦠 > Enveloped DNA viruses > Flashcards

Enveloped DNA viruses Flashcards

1
Q

What is the viruses in Enveloped viruses ?

A

1- Herpes simplex virus (HSVs)→ HSV-1 & HSV-2
2- Varicella-Zoster Virus (VZV)
3- Epstein-Barr Virus (EBV)
4- Cytomegalovirus (CMV)
5- Human Herpes Virus-8 (HHV-8) or Kaposi’s Sarcoma
6- Smallpox (variola) virus
7- Molluscum Contagiosum Virus (MCV)

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2
Q

enveloped double-stranded DNA viruses with icosahedral capsid ?

A

.Herpes Family: HSVs, VZV, EBV, CMV

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3
Q

Enumerate oncogenic viruses and the tumor they cause ?

A

1- HSV-2 → cervix cancer.
2- EBV →Burkitt’s lymphoma & nasopharyngeal carcinoma, thymic carcinoma.
3- HV-8 →Kaposi’s sarcoma.

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4
Q

HSV-1 is latent in the ?

A

trigeminal ganglia

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5
Q

HSV-2 is latent in the ?

A

lumbar ganglia

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6
Q

Both HSV-1 & HSV-2 have the ?

A

exact morphology ( الشكل الدقيق )

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7
Q

What os the Disease of HSV-1 ?

A 
1- Primary infection
2- acute Gingivostomatitis
3- Reoccurrence (reactivation)
4- Herpes Labialis (fever blisters or cold sores)
5- Herpetic Whitlow: (herpes infection of fingers)
6- Herpetic Keratoconjunctivitis
7- Encephalitis
8- Disseminated infections
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8
Q

Infected saliva, Lesions above the waist is in the ?

A

HSV-1

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9
Q

Sexually transmitted or from a maternal genital infection to a newborn, lesion are below waist is in the ?

A

HSV-2

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10
Q

Encephalitis: primary infection or a recurrence in ?

A

temporal lobe

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11
Q

Enumerate oncogenic viruses and the tumor they cause ?

A

1- HSV-2 → cervix cancer.
2- EBV →Burkitt’s lymphoma & nasopharyngeal carcinoma
3- HV-8 →Kaposi’s sarcoma.

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12
Q

Both HSV-1 & HSV-2 have the ?

A

exact morphology

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13
Q

HSV-1 latent in ?

A

trigeminal ganglia

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14
Q

HSV-2 latent in ?

A

lumbar ganglia

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15
Q

HSV-1is infected by ?

A

saliva

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16
Q

HSV-2 is infected by ?

A

Sexually transmitted

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17
Q

What is the Disease of HSV-1 ?

A 
1- Primary infection
2- acute Gingivostomatitis
3- Reoccurrence (reactivation)
4- Herpes Labialis (fever blisters or cold sores)
5- Herpetic Whitlow
6- Herpetic Keratoconjunctivitis
7- Encephalitis
8- Disseminated infections
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18
Q

Encephalitis: primary infection or a recurrence in ?

A

temporal lobe

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19
Q

What is the Disease of HSV-2 ?

A

1- Genital Herpes
2- Aseptic Meningitis
3- Neonatal Herpes

20
Q

What is the Direct diagnosis of Herpes simplex virus (HSVs)→ HSV-1 & HSV-2 ?

A

1- L/M : CPE (Multinucleated giant cells) ( Tzanck smear )

2- Intranuclear inclusion bodies Cowdry I.B

21
Q

What is the treatment of Herpes simplex virus (HSVs)→ HSV-1 & HSV-2 ?

A

Acyclovir

22
Q

Varicella-Zoster Virus (VZV) latent in ?

A

dorsal root ganglia

23
Q

What is the disease of Varicella-Zoster Virus (VZV) ?

A

1- Varicella ( CHICKEN POX )

2- Zoster ( shingles )

24
Q

What is the vaccine of Varicella-Zoster Virus (VZV) ?

A

1- Varivax & Zostavax

2- Shingrix

25
Q

What is the type of Varivax & Zostavax vaccine ?

A

live attenuated

26
Q

What is the kissing disease ?

A

Epstein-Barr Virus (EBV)

27
Q

Epstein-Barr Virus (EBV) latent is the ?

A

B-lymphocytes and oropharyngeal epithelium

28
Q

What is the Blood picture of Epstein-Barr Virus (EBV) ?

A

atypical lymphs

29
Q

heterophil positive ?

A

Epstein-Barr Virus (EBV)

30
Q

heterophil negative is ?

A

Cytomegalovirus (CMV)

31
Q

What is the transmission of Cytomegalovirus (CMV) ?

A

Vertical transmission: Transplacental

32
Q

Cytomegalovirus (CMV) first infects the URT→ become latent in ?

A

monocyte

33
Q

In Cytomegalovirus (CMV) the immunocopromized patients and newborn is acquired ?

A

Congenitlly

34
Q

What is the symptoms of Cytomegalic Inclusion Disease (CID) ?

A

1- Microcephaly

2- Purpuric rash

35
Q

What is the direct diagnosis of Cytomegalovirus (CMV) ?

A

CPE (Multinucleated giant cells) + intranuclear “Owl’s eye” I.B.

36
Q

intranuclear “Owl’s eye” I.B is in the ?

A

Cytomegalovirus (CMV)

37
Q

What is the Disease of Human Herpes Virus-8 (HHV-8) ?

A

Kaposi’s sarcoma

38
Q

Why the Smallpox (variola) virus is the first human disease in history that has been completely eradicated, because ?

A

1- It has one stable serotype (no variation)
2- Human only disease (no animal reservoir)
3- The disease is easily recognized

39
Q

In the Smallpox (variola) virus the the lesions are ?

A

all in the same stage

40
Q

What is the vaccine of Smallpox (variola) virus ?

A

vaccinia virus vaccine

41
Q

Smallpox (variola) virus is administrated by ?

A

skin scarification

42
Q

What is the Disease of Molluscum Contagiosum Virus (MCV) ?

A

molluscum contagiosum

43
Q

Molluscum Contagiosum Virus (MCV) have a characteristic ?

A

cup-shaped ( umbilicated) crater with a white core.

44
Q

Molluscum Contagiosum Virus (MCV) Treated by ?

A

Surgical removal

45
Q

Epstein -Bar virus ( EBV ) latent in ?

A

B-lymphocytes

46
Q

Cytomegalo virus (CMV) is latent in ?

A

Monocyte

Micro 🦠 (41 decks)

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