Enveloped DNA viruses

Question 1

What is the viruses in Enveloped viruses ?

Answer 1

1- Herpes simplex virus (HSVs)→ HSV-1 & HSV-2
2- Varicella-Zoster Virus (VZV)
3- Epstein-Barr Virus (EBV)
4- Cytomegalovirus (CMV)
5- Human Herpes Virus-8 (HHV-8) or Kaposi’s Sarcoma
6- Smallpox (variola) virus
7- Molluscum Contagiosum Virus (MCV)

Question 2

enveloped double-stranded DNA viruses with icosahedral capsid ?

Answer 2

.Herpes Family: HSVs, VZV, EBV, CMV

Question 3

Enumerate oncogenic viruses and the tumor they cause ?

Answer 3

1- HSV-2 → cervix cancer.
2- EBV →Burkitt’s lymphoma & nasopharyngeal carcinoma, thymic carcinoma.
3- HV-8 →Kaposi’s sarcoma.

Question 4

HSV-1 is latent in the ?

Answer 4

trigeminal ganglia

Question 5

HSV-2 is latent in the ?

Answer 5

lumbar ganglia

Question 6

Both HSV-1 & HSV-2 have the ?

Answer 6

exact morphology ( الشكل الدقيق )

Question 7

What os the Disease of HSV-1 ?

Answer 7

1- Primary infection
2- acute Gingivostomatitis
3- Reoccurrence (reactivation)
4- Herpes Labialis (fever blisters or cold sores)
5- Herpetic Whitlow: (herpes infection of fingers)
6- Herpetic Keratoconjunctivitis
7- Encephalitis
8- Disseminated infections

Question 8

Infected saliva, Lesions above the waist is in the ?

Answer 8

HSV-1

Question 9

Sexually transmitted or from a maternal genital infection to a newborn, lesion are below waist is in the ?

Answer 9

HSV-2

Question 10

Encephalitis: primary infection or a recurrence in ?

Answer 10

temporal lobe

Question 11

Enumerate oncogenic viruses and the tumor they cause ?

Answer 11

1- HSV-2 → cervix cancer.
2- EBV →Burkitt’s lymphoma & nasopharyngeal carcinoma
3- HV-8 →Kaposi’s sarcoma.

Question 12

Both HSV-1 & HSV-2 have the ?

Answer 12

exact morphology

Question 13

HSV-1 latent in ?

Answer 13

trigeminal ganglia

Question 14

HSV-2 latent in ?

Answer 14

lumbar ganglia

Question 15

HSV-1is infected by ?

Answer 15

saliva

Question 16

HSV-2 is infected by ?

Answer 16

Sexually transmitted

Question 17

What is the Disease of HSV-1 ?

Answer 17

1- Primary infection
2- acute Gingivostomatitis
3- Reoccurrence (reactivation)
4- Herpes Labialis (fever blisters or cold sores)
5- Herpetic Whitlow
6- Herpetic Keratoconjunctivitis
7- Encephalitis
8- Disseminated infections

Question 18

Encephalitis: primary infection or a recurrence in ?

Answer 18

temporal lobe

Question 19

What is the Disease of HSV-2 ?

Answer 19

1- Genital Herpes
2- Aseptic Meningitis
3- Neonatal Herpes

Question 20

What is the Direct diagnosis of Herpes simplex virus (HSVs)→ HSV-1 & HSV-2 ?

Answer 20

1- L/M : CPE (Multinucleated giant cells) ( Tzanck smear )

2- Intranuclear inclusion bodies Cowdry I.B

Question 21

What is the treatment of Herpes simplex virus (HSVs)→ HSV-1 & HSV-2 ?

Answer 21

Acyclovir

Question 22

Varicella-Zoster Virus (VZV) latent in ?

Answer 22

dorsal root ganglia

Question 23

What is the disease of Varicella-Zoster Virus (VZV) ?

Answer 23

1- Varicella ( CHICKEN POX )

2- Zoster ( shingles )

Question 24

What is the vaccine of Varicella-Zoster Virus (VZV) ?

Answer 24

1- Varivax & Zostavax

2- Shingrix

Question 25

What is the type of Varivax & Zostavax vaccine ?

Answer 25

live attenuated

Question 26

What is the kissing disease ?

Answer 26

Epstein-Barr Virus (EBV)

Question 27

Epstein-Barr Virus (EBV) latent is the ?

Answer 27

B-lymphocytes and oropharyngeal epithelium

Question 28

What is the Blood picture of Epstein-Barr Virus (EBV) ?

Answer 28

atypical lymphs

Question 29

heterophil positive ?

Answer 29

Epstein-Barr Virus (EBV)

Question 30

heterophil negative is ?

Answer 30

Cytomegalovirus (CMV)

Question 31

What is the transmission of Cytomegalovirus (CMV) ?

Answer 31

Vertical transmission: Transplacental

Question 32

Cytomegalovirus (CMV) first infects the URT→ become latent in ?

Answer 32

monocyte

Question 33

In Cytomegalovirus (CMV) the immunocopromized patients and newborn is acquired ?

Answer 33

Congenitlly

Question 34

What is the symptoms of Cytomegalic Inclusion Disease (CID) ?

Answer 34

1- Microcephaly | 2- Purpuric rash

Question 35

What is the direct diagnosis of Cytomegalovirus (CMV) ?

Answer 35

CPE (Multinucleated giant cells) + intranuclear "Owl's eye” I.B.

Question 36

intranuclear "Owl's eye” I.B is in the ?

Answer 36

Cytomegalovirus (CMV)

Question 37

What is the Disease of Human Herpes Virus-8 (HHV-8) ?

Answer 37

Kaposi’s sarcoma

Question 38

Why the Smallpox (variola) virus is the first human disease in history that has been completely eradicated, because ?

Answer 38

1- It has one stable serotype (no variation) 2- Human only disease (no animal reservoir) 3- The disease is easily recognized

Question 39

In the Smallpox (variola) virus the the lesions are ?

Answer 39

all in the same stage

Question 40

What is the vaccine of Smallpox (variola) virus ?

Answer 40

vaccinia virus vaccine

Question 41

Smallpox (variola) virus is administrated by ?

Answer 41

skin scarification

Question 42

What is the Disease of Molluscum Contagiosum Virus (MCV) ?

Answer 42

molluscum contagiosum

Question 43

Molluscum Contagiosum Virus (MCV) have a characteristic ?

Answer 43

cup-shaped ( umbilicated) crater with a white core.

Question 44

Molluscum Contagiosum Virus (MCV) Treated by ?

Answer 44

Surgical removal

Question 45

Epstein -Bar virus ( EBV ) latent in ?

Answer 45

B-lymphocytes

Question 46

Cytomegalo virus (CMV) is latent in ?

Answer 46

Monocyte