Fungi Flashcards

1
Q

When grown in tissues (inside the body) or culture media at ( 37°C ) ?

A

Yeast Form

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2
Q

When present in nature (i.e. free living) or grown on culture media at 25°C (room temp) ?

A

Filamentous Form

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3
Q

In the fungi microscopic stained by ?

A

lactophenol cotton blue, culture on SDA agar

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4
Q

Superficial mycosis cause?

A

Tinea Versicolor disease

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5
Q

Tinea Versicolor disease is caused by ?

A

Malassezia furfur

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6
Q

Superficial mycosis→ Tinea Versicolor disease the skin infection of the ?

A

stratum corneum

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7
Q

Superficial mycosis→ Tinea Versicolor disease is Examination under Wood’s light shows ?

A

orange fluorescence

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8
Q

What is the fungi that show in skin scales Spaghetti and meat balls appearance ?

A

Malassezia furfur

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9
Q

Cutaneous Mycosis cause ?

A

Tinea or ringworm diseases ( Dermatophytes: (filamentous fungi))

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10
Q

Typical ringworm or tinea Dermatophytes: (filamentous fungi)

is an ?

A

inflamed circular border containing papules and vesicles

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11
Q

Tinea Barbie ?

A

on chin

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12
Q

Tinea corporis ?

A

on trunk and body

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13
Q

Tinea capitis ?

A

on scalp

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14
Q

Tinea ungium (Onychomycosis) ?

A

on nails

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15
Q

Tinea pedis (Athlete’s foot) ?

A

on foot

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16
Q

What is the Examination of Tinea or ringworm diseases ?

A

hair by Wood’s light (UV): Microsporum that infects hairs give green fluorescence

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17
Q

Endothrix: Fungus inside hair shaft by ?

A

Trichophyton

18
Q

Ectothrix: Fungus around hair shaft by ?

A

Microsporum

19
Q

What is the Culture of Tinea or ringworm diseases Dermatophytes: (filamentous fungi) )

A

On Sabouraud’s agar SDA

20
Q

Subcutaneous Mycosis can cause ?

A

Sporotrichosis (Rose-picker’s disease)

21
Q

Sporotrichosis (Rose-picker’s disease) Caused by ?

A

Sporothrix schenkii (Dimorphic)

22
Q

What is the culture of Sporotrichosis (Rose-picker’s disease) ?

A

On SDA→ hyphae (a daisy appearance ).

23
Q

a daisy appearance in the ?

A

Sporotrichosis (Rose-picker’s disease)

24
Q

Subcutaneous mycosis cuase ?

A

Mycetoma & chromoblastomycosis

25
Systemic Mycosis They are caused by ?
dimorphic fungi
26
Histoplasmosis (TB-like) is ?
Mycosis Histoplasma capsulatum .
27
Wjat is the stain for bone marrow in the Systemic Mycosis ?
Giemsa stain
28
What is the treatment of Pulmonary affection in Systemic Mycosis ?
Oral azoles
29
What is the treatment of Disseminated disease in the Systemic Mycosis ?
IV amphotrecim B
30
Cryptococcous neoformans (Capsulated yeast) cause ?
Chronic meningitis
31
Aspergillus (filamentous)→ cause infection in ?
patients with marked neutropenia
32
disrupt cell membrane, directly attack ergosterol ?
Amphotericin B
33
Attack ergosterol in cell membrane ?
Azoles
34
attack beta-glucan in cell wall ?
Echinocadins
35
inhibit DNA synthesis ?
flucytosine
36
disrupts mitotic spindle ?
Griseofulvin
37
SDA Colonies are whitish and highly mucoid in ?
Cryptococcous neoformans (Capsulated yeast)
38
Treatment IV amphotrecim B in ?
1-Disseminated disease: IV amphotrecim B in Systemic Mycosis 2- Aspergilloma 3-Systemic Candida
39
Treatment azoles for ?
``` 1-Malassezia furfur 2- local treatment of Dermatophytes 3-Sporothrix schenkii 4-Pulmonary affection of Systemic Mycosis 5-Invasive aspergillosis ```
40
“ crushed ping-pong ball ” appearance .
Pneumocystis Jiroveci
41
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