Bordetella pertussis Flashcards
1
Q
Describe two effects of pertussis toxin ?
A
1- Increase sensitivity to histamine = bronchospasm
2- inhibits normal cellular signaling
2
Q
What is the tests of Bordetella pertussis ?
A
1- Polymerase chain reaction (PCR)
2- Direct fluorescent antibody (FA)
3
Q
What is tje specimen of Bordetella pertussis السعال الديكي ?
A
saline nasal wash, cough plate
4
Q
What is the Disease of Bordetella pertussis ?
A
acute tracheobronchitis:
1- Catarrhal stage
2- Paroxysmal stage
5
Q
severe successive attacks of cough lasting weeks, followed by a deep inspiration (characteristic whoop)?
A
Paroxysmal stage
6
Q
( characteristic whoop ) in ?
A
Paroxysmal stage
7
Q
What is the vaccine of bordetella pertussis ?
A
1- DTap, Tdap , type: Acellular vaccine
2- pertussis vaccine , Type: killed vaccine
