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Micro 🦠 > Hepatitis Viruses > Flashcards

Hepatitis Viruses Flashcards

1
Q

What is the Ss RNA of Hepatitis Viruses ?

A 
(H AV)
(HCV)
(HDV)
(HEV)
كلهم ما عدا B
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2
Q

dsDNS Hepatitis Viruses ?

A

HBV

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3
Q

What is the non envelope Hepatitis Viruses amd source is feces ?

A

HAV

HEV

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4
Q

What is the symptoms of Hepatitis Virus?

A

jaundice, dark urine and pale stool.

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5
Q

What is the Structure of Hepatitis Virus A ?

A

1- non-enveloped ss RNA virus

2- It has one serotype.

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6
Q

HAV is transmitted by the fecal-

oral route ?

A

HAV , HEV

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7
Q

What is the most frequently

infected group of HAV Virus ?

A

Children

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8
Q

What is the vaccine of Hepatitis A and what is the type of it !

A

HAV vaccine , type : Killed

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9
Q

What is the incubation period of Hepatitis A ?

A

0.5- 1 month.

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10
Q

What is the incubation period of Hepatitis E ?

A

0.5- 2 months

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11
Q

non-enveloped , ssRNA virus ?

A

HEPATITIS E VIRUS (HEV)

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12
Q

What is the type of Hepatitis virus is high mortality rates among pregnant women ?

A

HEPATITIS E VIRUS (HEV)

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13
Q

HBsAg ?

A

Infection HBV

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14
Q

No HBsAg ?

A

No infection

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15
Q

The presence of …….. is indicative of the

presence of the HBV ?

A

HBsAg

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16
Q

What is the important for diagnosis of HBV in infection and for vaccine preparation ?

A

HBsAg

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17
Q

What is the Transmission of HBV ?

A

1- Blood transfusions, blood products
2- organ donation
3- Intravenous drug abusers
4- Needle stick or sharp injuries

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18
Q 
In the HBV the :
HBs Ag = negative
antiHBc= negative
antiHBs = negative 
This is ?
A

susceptible ما دخله ال HBV

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19
Q 
The HBV is : 
HBsAg = negative
antiHBc = positive
antiHBs = positive 
is ?
A

immune due to natural infection

صارت له مناعه بس بسبب انه اصيب بالفيروس من قبل

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20
Q 
In the HBV the : 
HBsAg = negative
antiHBc = negative
antiHBs = positive
Is ?
A

immune due to vaccine

صارت له مناعه بسبب اللقاح

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21
Q 
In the HBV the : 
HBsAg = positive
antiHBc = positive
IgM antiHBc = positive
antiHBs = negative
Is ?
A

acutely infected

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22
Q 
In the HBV the : 
HBsAg = positive
antiHBc = positive
IgM antiHBc = negative
antiHBs = negative 
Is ?
A

Chronically infected

23
Q

What is the vaccine of HBV in the Active Immunization ?

A

Recombinant HBV Vaccine

24
Q

Hwat is the ssRNA defective virus , and non envelope ?

A

HDV , HCV

25
Q

Hepatitis D is transmitted principally by ?

A

percutaneous exposure , mainly blood transfusion

26
Q

HDV and HBV may concurrently infect a susceptible

host, called ?

A

coinfection

27
Q

Alternatively, a person who is already a chronic HBsAg carrier can be ……… with HDV.

A

superinfected

28
Q

occurs more frequently than is seen with HBV alone ?

A

fulminant hepatic failure

29
Q

What is the Laboratory Diagnosis of Hepatitis D ?

A

Detect delta antigen or IgM antibodies

30
Q

What is the Transmission of HDV ?

A

1- Blood transfusions, blood products
2- organ donation
3- Intravenous drug abusers

31
Q

What is the Incubation period of HDV ?

A

0.5 – 6 months

32
Q

What is the test of HDV that does not distinguish between acute, chronic or resolved infection ?

A

ELISA

33
Q

In the HDV thw Seroconversion be delayed up to ?

A

6 months

34
Q

What is the vaccine of Hepatitis A (HAV) ?

A

Killed HAV vaccine

35
Q

What is the type of hepatitis virus that resistant to lipid solvents (ethanol), extremes of pH (pH 3 - gastric acidity) ?

A

Hepatitis A (HAV)

36
Q

What is the PH of Hepatitis A (HAV) ?

A

resistant to ( pH 3 - gastric acidity )

37
Q

What is the Prevention of Hepatitis B (HBV) ?

A

1- Active Immunization: Recombinant HBV Vaccine

2- Passive Immunization: Hepatitis B immunoglobulin (HBIG)

38
Q

Hepatitis D (HDV) is transmitted principally by ?

A

percutaneous exposure, mainly blood transfusion

39
Q

What is the Structure of enveloped ss RNA virus , Have a genetic variation ( hypervariable) ?

A

Hepatitis C (HCV)

40
Q

T-cell in Hepatitis C (HCV) is ?

A

resolution of acute HCV infection

41
Q

B-cell in Hepatitis C (HCV) is ?

A

chronic HCV infection.

42
Q

What is the Transmission of Hepatitis C (HCV) ?

A

1- Blood transfusions,→ so, Screening of blood donor by RT-PCR is important.
2- Vertical and Perinatal transmission
3- sexually

43
Q

What is the non-enveloped single-stranded RNA virus of Hepatitis viruses?

A

1- Hepatitis A (HAV)

2- Hepatitis E (HEV)

44
Q

What is the enveloped ss RNA virus of Hepatitis viruses ?

A

1- Hepatitis D (HDV)

2- Hepatitis C (HCV)

45
Q

What is the Enveloped double-stranded DNA virus ?

A

Hepatitis B (HBV)

46
Q

What is the different between Hepatitis viruses ?

A

Hepatitis A (HAV) :
non-enveloped single-stranded RNA virus.
Fecal-oral transmission
Children are the most frequently infected group.
Killed HAV vaccine

Hepatitis E (HEV): 
non-enveloped single-stranded RNA virus
Fecal-oral transmission
pregnant women
No vaccine

Hepatitis B (HBV):
Enveloped double-stranded DNA virus
Active Immunization: Recombinant HBV Vaccine
Passive Immunization: Hepatitis B immunoglobulin (HBIG)

Hepatitis D (HDV):
HDV is a single-stranded RNA enveloped
transmitted principally by percutaneous exposure, mainly blood transfusion

Hepatitis C (HCV): 
enveloped ss RNA virus.
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54
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