Hepatitis Viruses Flashcards

1
Q

What is the Ss RNA of Hepatitis Viruses ?

A
(H AV)
(HCV)
(HDV)
(HEV)
كلهم ما عدا B
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2
Q

dsDNS Hepatitis Viruses ?

A

HBV

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3
Q

What is the non envelope Hepatitis Viruses amd source is feces ?

A

HAV

HEV

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4
Q

What is the symptoms of Hepatitis Virus?

A

jaundice, dark urine and pale stool.

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5
Q

What is the Structure of Hepatitis Virus A ?

A

1- non-enveloped ss RNA virus

2- It has one serotype.

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6
Q

HAV is transmitted by the fecal-

oral route ?

A

HAV , HEV

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7
Q

What is the most frequently

infected group of HAV Virus ?

A

Children

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8
Q

What is the vaccine of Hepatitis A and what is the type of it !

A

HAV vaccine , type : Killed

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9
Q

What is the incubation period of Hepatitis A ?

A

0.5- 1 month.

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10
Q

What is the incubation period of Hepatitis E ?

A

0.5- 2 months

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11
Q

non-enveloped , ssRNA virus ?

A

HEPATITIS E VIRUS (HEV)

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12
Q

What is the type of Hepatitis virus is high mortality rates among pregnant women ?

A

HEPATITIS E VIRUS (HEV)

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13
Q

HBsAg ?

A

Infection HBV

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14
Q

No HBsAg ?

A

No infection

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15
Q

The presence of …….. is indicative of the

presence of the HBV ?

A

HBsAg

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16
Q

What is the important for diagnosis of HBV in infection and for vaccine preparation ?

A

HBsAg

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17
Q

What is the Transmission of HBV ?

A

1- Blood transfusions, blood products
2- organ donation
3- Intravenous drug abusers
4- Needle stick or sharp injuries

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18
Q
In the HBV the :
HBs Ag = negative
antiHBc= negative
antiHBs = negative 
This is ?
A

susceptible ما دخله ال HBV

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19
Q
The HBV is : 
HBsAg = negative
antiHBc = positive
antiHBs = positive 
is ?
A

immune due to natural infection

صارت له مناعه بس بسبب انه اصيب بالفيروس من قبل

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20
Q
In the HBV the : 
HBsAg = negative
antiHBc = negative
antiHBs = positive
Is ?
A

immune due to vaccine

صارت له مناعه بسبب اللقاح

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21
Q
In the HBV the : 
HBsAg = positive
antiHBc = positive
IgM antiHBc = positive
antiHBs = negative
Is ?
A

acutely infected

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22
Q
In the HBV the : 
HBsAg = positive
antiHBc = positive
IgM antiHBc = negative
antiHBs = negative 
Is ?
A

Chronically infected

23
Q

What is the vaccine of HBV in the Active Immunization ?

A

Recombinant HBV Vaccine

24
Q

Hwat is the ssRNA defective virus , and non envelope ?

25
Hepatitis D is transmitted principally by ?
percutaneous exposure , mainly blood transfusion
26
HDV and HBV may concurrently infect a susceptible | host, called ?
coinfection
27
Alternatively, a person who is already a chronic HBsAg carrier can be ……… with HDV.
superinfected
28
occurs more frequently than is seen with HBV alone ?
fulminant hepatic failure
29
What is the Laboratory Diagnosis of Hepatitis D ?
Detect delta antigen or IgM antibodies
30
What is the Transmission of HDV ?
1- Blood transfusions, blood products 2- organ donation 3- Intravenous drug abusers
31
What is the Incubation period of HDV ?
0.5 – 6 months
32
What is the test of HDV that does not distinguish between acute, chronic or resolved infection ?
ELISA
33
In the HDV thw Seroconversion be delayed up to ?
6 months
34
What is the vaccine of Hepatitis A (HAV) ?
Killed HAV vaccine
35
What is the type of hepatitis virus that resistant to lipid solvents (ethanol), extremes of pH (pH 3 - gastric acidity) ?
Hepatitis A (HAV)
36
What is the PH of Hepatitis A (HAV) ?
resistant to ( pH 3 - gastric acidity )
37
What is the Prevention of Hepatitis B (HBV) ?
1- Active Immunization: Recombinant HBV Vaccine | 2- Passive Immunization: Hepatitis B immunoglobulin (HBIG)
38
Hepatitis D (HDV) is transmitted principally by ?
percutaneous exposure, mainly blood transfusion
39
What is the Structure of enveloped ss RNA virus , Have a genetic variation ( hypervariable) ?
Hepatitis C (HCV)
40
T-cell in Hepatitis C (HCV) is ?
resolution of acute HCV infection
41
B-cell in Hepatitis C (HCV) is ?
chronic HCV infection.
42
What is the Transmission of Hepatitis C (HCV) ?
1- Blood transfusions,→ so, Screening of blood donor by RT-PCR is important. 2- Vertical and Perinatal transmission 3- sexually
43
What is the non-enveloped single-stranded RNA virus of Hepatitis viruses?
1- Hepatitis A (HAV) | 2- Hepatitis E (HEV)
44
What is the enveloped ss RNA virus of Hepatitis viruses ?
1- Hepatitis D (HDV) | 2- Hepatitis C (HCV)
45
What is the Enveloped double-stranded DNA virus ?
Hepatitis B (HBV)
46
What is the different between Hepatitis viruses ?
Hepatitis A (HAV) : non-enveloped single-stranded RNA virus. Fecal-oral transmission Children are the most frequently infected group. Killed HAV vaccine ``` Hepatitis E (HEV): non-enveloped single-stranded RNA virus Fecal-oral transmission pregnant women No vaccine ``` Hepatitis B (HBV): Enveloped double-stranded DNA virus Active Immunization: Recombinant HBV Vaccine Passive Immunization: Hepatitis B immunoglobulin (HBIG) Hepatitis D (HDV): HDV is a single-stranded RNA enveloped transmitted principally by percutaneous exposure, mainly blood transfusion ``` Hepatitis C (HCV): enveloped ss RNA virus. ```
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