Sperm entry and fertilization Flashcards

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1
Q

Step 1) Sperm entry in oocyte (b/c sperm pushes though the corona radiata &digestive enzymes disrupt the zone pellucida) This causes the oocyte to release…

A

Calcium! Which triggers:

  • Release of cortical granules to harden zone pellucida
  • removal of sperm receptors
  • ultimately prevents polyspermy
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2
Q

step 2) Fertilization occurs. What does the secondary oocyte do now

A

It completes meiosis 2 gets rid of another polar body. The nuclei of sperm and egg fuse causing the zygote, The dna replicates and it begins mitosis

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3
Q

What are the 5 Stages of development (In the 1st trimester)

A

1) Cleavage 2) Implantation 3) gastrulation 4) placentation 5) Embryogenesis

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4
Q

what is cleavage

A

Zygote divides w/o growth, hatches from zone pellucid and goes to implant

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5
Q

What is implantation

A

contact w/ endometrium, the outer layer is the trophoblast which will fuse to the endometrium and the inside will form the fetus. Buries itself. Has yolk sac (first Blood cells, digestive, egg&sperm and umbilical cord) amniotic cavity and embryonic disk.

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6
Q

What is gastrulation

A

Emrionic disc form 3 cell layers.
ectoderm: integument, nervous
Mesoderm: muscular, skeletal
Endoderm: endocrine, resp, difest, urinary, reproductive

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7
Q

What is placentation

A

Chorionic villi and pool of maternal blood become the placenta.

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8
Q

What does early placenta secrete

A

Human Chorionic gonadotrophic hormone to maintain compus lutem

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9
Q

What does the mature placenta secrete

A
  • Estrogen and progesterone
  • human placental lactogen: mom use fatty acid and glucose for fetus, develop mammary glands
  • human chorionic thyrotropin: increase maternal metabolism
  • relaxin: to stretch flexible smooth muscle.
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10
Q

What is embryogenesis

A

All major organ systems start

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11
Q

2nd trimester

A

Growth and development of organ system

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12
Q

3rd trimester

A

weight, mylination and organs complete

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13
Q

What are teratogens

A

thing that disrupt fetal development: damage cells and effect DNA structure. Radiation, chemo, drugs, antibiotic, alcohol, and smoke. In the 1st trimester it effects ll organs but in 2nd or 3rd it’ll effect only specific organs

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