Soft Tissue Sarcoma Flashcards

1
Q

when are peripheral nerve sheath tumors not considered soft tissue sarcoma?

A

when they occur with a macroscopic nerve root because these are more difficult to treat due to location

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2
Q

can canine soft tissue sarcomas arise from any anatomical site in the body?

A

yes

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3
Q

if a biopsy is done, where must the track be?

A

in an area that will be surgically excised

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4
Q

is marginal excision recommended?

A

no

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5
Q

what is the metastatic rate for intermediate and low-grade soft tissue sarcomas?

A

<10%

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6
Q

what are the margins like with soft tissue sarcoma surgery?

A

3 cm

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7
Q

what are tumor cells at the margin of excised tissue associated with?

A

consistently with decreased rates of survival

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8
Q

what is low grade tumor recurrence with incomplete resection?

A

35%

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9
Q

what can pre-operative radiation help with?

A

“sterilize” perimeter and potentially allow for a smaller surgery

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10
Q

what is the metastatic rate of feline injection site sarcomas?

A

30%

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11
Q

what does canine soft tissue sarcoma arise from?

A

fibroblasts

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12
Q

what neoplasias are included in soft tissue sarcoma?

A

fibrosarcoma
myxosarcoma
perivascular wall tumor- hemangiopericytoma
peripheral nerve sheath tumor

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13
Q

how do soft tissue sarcomas metastasize?

A

hematogenous route

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14
Q

can cytology grade sarcomas?

A

no
biopsy may be able to

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15
Q

what is excisional biopsy/marginal excision?

A

neoplasia is removed with no margin of grossly normal tissue

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16
Q

what is canine soft tissue sarcoma surrounded by?

A

pseudocapsule
tumor cells can extend far beyond capsule

17
Q

what is a margin?

A

amount of skin and tissue removed around the circumference of the tumor

18
Q

what determines differentiation score?

A

1: well differentiated, resemble normal mesenchymal tissue
2: poorly differentiated
3: undifferentiated, cannot identify tissue of origin

19
Q

what is median survival following complete excision of a low or intermediate grade soft tissue sarcoma?

A

> 1500 days

20
Q

what are injection site sarcomas found to contain?

A

gray-brown foreign substance: aluminum

21
Q

when should you suspect feline injection site sarcoma?

A

persists >3months
large than 2cm
increasing in size one month post injection

22
Q

what is feline post traumatic ocular sarcoma?

A

syndrome where a sarcoma develops in the eye post trauma or chronic uveitis

23
Q

what is rate of recurrence with feline injection site sarcomas directly related to?

A

success of first surgery