Small Bowel Tumours Flashcards

1
Q

What is a carcinoid tumour?

A

Slow-growing neuroendocrine tumour

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2
Q

What cells do carcinoid tumours arise form?

A

Enterchromaffin cells of intestine

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3
Q

Where are carcinoid tumours most commonly found?

A

Appendix & terminal ileum

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4
Q

Where do carcinoid tumours usually metastasis to?

A

Liver

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5
Q

Investigations for SI tumours?

A
  • Serum chromogranin A
  • 24h urine secretion of 5-hydroxyindoleacetic acid
  • Radiological imaging to check for Mets
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6
Q

Management of SI tumours?

A
  • Surgical resection

- Octreotide/lanreotide (somatostatin analogues) inhibit the release of hormones alleviating symptoms

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7
Q

3 types of SI tumours?

A
  • Adenocarcinoma
  • Lymphoma
  • Carcinoid tumours
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8
Q

Primary tumours are more common than secondary. True or false?

A

FALSE

Primary tumors are very rare, secondary are much more common

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9
Q

Where is adenocarcinoma most commonly found?

A

Duodenum & jejunum

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10
Q

Where is the primary tumor in adenocarcinoma usually found?

A

Small bowel

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11
Q

What is a predisposing factor for adenocarcioma?

A

Crohn’s

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12
Q

Management for adenocarcinoma?

A

Surgical resection + radio + chemo

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13
Q

Where is lymphoma most commonly found?

A

Ileum

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14
Q

What is the most common type of lymphoma?

A

B cell arising from MALT

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15
Q

Management of lymphoma?

A

Surgical resection + radio + chemo

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16
Q

Symptoms of carcinoid tumours?

A

Asymptomatic

17
Q

What does carcinoid syndrome involve and when is it most likely to occur?

A

-Spontaneous flushing, diarrhoea, SOB/wheeze, pulmonary stenosis or tricuspid incompetence

18
Q

What is produced by carcinoid tumors?

A

Serotonin which increases motility and peristalsis, bronchoconstriction and can produce collagen via fibroblasts in the heart