Slideshow 3 Flashcards

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1
Q

What does SGR stand for ? mainly what is it named after ?

A

named stay green, named after the mutant state

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2
Q

so SGR+/SGR+ is ?

A

Like A/A

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3
Q

so SGR-/SGR- is ?

A

like a/a

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4
Q

What happens when SGR+ doesn’t work correctly?

A

If wont be able to degrade chlorophyll , meaning they will look green

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5
Q

Does geno determine pheno or the other way around?

A

genotype can help determine the phenotype

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6
Q

why is yellow dominant in the pea plants ?

A

because one dose of wild type protein is enough to effectively remove chlorophll

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7
Q

what is pah referring to

A

phenylketonuria

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8
Q

what is the mutations effect based on?

A

mainly based on where it actually occurs on a chromosome

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9
Q

Intergenic def

A

area between genes

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10
Q

intragenic def

A

area within a gene

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11
Q

intron def

A

within a protein coding gene, a region that dows not code for amino acid

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12
Q

exon def

A

within a protein coding gene, a region that DOES code for amino acids

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13
Q

What are the two extreme mutations

A

silent and null mutation

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14
Q

silent mutation def

A

has no effect on the protein sequence coded

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15
Q

null mutation def

A

eliminates function of the protein coded for by the gene

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16
Q

what does structure dictate

A

function

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17
Q

transcription does what

A

DNA to MRNA

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18
Q

translation does what

A

turns MRNA to protein

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19
Q

do all mutations affect funtion?

A

no

20
Q

what do ALL mutations do

A

change the DNA sequence

21
Q

Mendelian diploid transmission genetics means what?

A

detthat 1 gene affects phenotype (think about pea plants)

22
Q

Once a mutation occurs, what can we classify it as ?

A

silent or null

23
Q

What does multiple alleles mean

A

when 4 alleles affect and complete the color gene (think of the rabbits)

24
Q

Haplosufficiency def

A

a single wild type allele is sufficient for wild-type phenotype

25
Q

in haplosufficient phenotypes what is the heterogygous phenotype the same as

A

same as wild type

26
Q

haploinsufficiency def

A

a single wild-type allele is insufficient for wild-type phenotype

27
Q

in haploinsufficiency phenotypes what is the heterogygous phenotype the same as

A

same as mutant

28
Q

Dominant negative mutation /allele def

A

mutant protein product interferes with the function of the wild-type protein product

29
Q

can recessive allels be wild type ?

A

YES

30
Q

can dominant alleles be mutant?

A

YES

31
Q

Dominant negative mutation quick summary:

A

They need two good functional proteins in order to work

32
Q

What are the 2 exceptions to complete dominance

A

Codominance and Incomplete

33
Q

codominance def

A

in the heterozygote we see a third phenotype and both homozygous phenotypes show up seperately

34
Q

incomplete dominance def

A

in the heterozygote we see a third phenotype which is a mixture of the homozygous phenotypes.

35
Q

is there always complete dominance ?

A

no

36
Q

Epistasis def

A

aka gene interaction

37
Q

Example of epistasis

A

allele A affects phenotype differently depending on the genotype at another gene

38
Q

under episatis , what is the effect of a genotype at one gene contingent upon

A

the genotype at one of more other genes

39
Q

phenotype getting determined by variation @2 or more genes is in what

A

Epistasis

40
Q

melanocytes def

A

affects color

41
Q

eumelanin def

A

a darkish pigment found in hair and skin

42
Q

In dogs what is black represented by

A

B/_ ; E/_

43
Q

in dogs what is brown represented by

A

b/b ; E/_

44
Q

in dogs what is a yellow dog with a pink nose represented as

A

b/b ; e/e

45
Q

in dogs what is a yellow dog with a black nose represented as

A

B/_ ; e/e

46
Q
A