Slideshow 3 Flashcards

1
Q

What does SGR stand for ? mainly what is it named after ?

A

named stay green, named after the mutant state

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2
Q

so SGR+/SGR+ is ?

A

Like A/A

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3
Q

so SGR-/SGR- is ?

A

like a/a

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4
Q

What happens when SGR+ doesn’t work correctly?

A

If wont be able to degrade chlorophyll , meaning they will look green

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5
Q

Does geno determine pheno or the other way around?

A

genotype can help determine the phenotype

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6
Q

why is yellow dominant in the pea plants ?

A

because one dose of wild type protein is enough to effectively remove chlorophll

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7
Q

what is pah referring to

A

phenylketonuria

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8
Q

what is the mutations effect based on?

A

mainly based on where it actually occurs on a chromosome

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9
Q

Intergenic def

A

area between genes

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10
Q

intragenic def

A

area within a gene

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11
Q

intron def

A

within a protein coding gene, a region that dows not code for amino acid

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12
Q

exon def

A

within a protein coding gene, a region that DOES code for amino acids

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13
Q

What are the two extreme mutations

A

silent and null mutation

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14
Q

silent mutation def

A

has no effect on the protein sequence coded

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15
Q

null mutation def

A

eliminates function of the protein coded for by the gene

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16
Q

what does structure dictate

A

function

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17
Q

transcription does what

A

DNA to MRNA

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18
Q

translation does what

A

turns MRNA to protein

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19
Q

do all mutations affect funtion?

20
Q

what do ALL mutations do

A

change the DNA sequence

21
Q

Mendelian diploid transmission genetics means what?

A

detthat 1 gene affects phenotype (think about pea plants)

22
Q

Once a mutation occurs, what can we classify it as ?

A

silent or null

23
Q

What does multiple alleles mean

A

when 4 alleles affect and complete the color gene (think of the rabbits)

24
Q

Haplosufficiency def

A

a single wild type allele is sufficient for wild-type phenotype

25
in haplosufficient phenotypes what is the heterogygous phenotype the same as
same as wild type
26
haploinsufficiency def
a single wild-type allele is insufficient for wild-type phenotype
27
in haploinsufficiency phenotypes what is the heterogygous phenotype the same as
same as mutant
28
Dominant negative mutation /allele def
mutant protein product interferes with the function of the wild-type protein product
29
can recessive allels be wild type ?
YES
30
can dominant alleles be mutant?
YES
31
Dominant negative mutation quick summary:
They need two good functional proteins in order to work
32
What are the 2 exceptions to complete dominance
Codominance and Incomplete
33
codominance def
in the heterozygote we see a third phenotype and both homozygous phenotypes show up seperately
34
incomplete dominance def
in the heterozygote we see a third phenotype which is a mixture of the homozygous phenotypes.
35
is there always complete dominance ?
no
36
Epistasis def
aka gene interaction
37
Example of epistasis
allele A affects phenotype differently depending on the genotype at another gene
38
under episatis , what is the effect of a genotype at one gene contingent upon
the genotype at one of more other genes
39
phenotype getting determined by variation @2 or more genes is in what
Epistasis
40
melanocytes def
affects color
41
eumelanin def
a darkish pigment found in hair and skin
42
In dogs what is black represented by
B/_ ; E/_
43
in dogs what is brown represented by
b/b ; E/_
44
in dogs what is a yellow dog with a pink nose represented as
b/b ; e/e
45
in dogs what is a yellow dog with a black nose represented as
B/_ ; e/e
46