Slideshow 16 Flashcards

1
Q

condensation of chromatin leads to what

A

solenoids

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2
Q

assembly of the nucleosome results in what

A

histone tails

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3
Q

epigenic marks are what

A

chemical modifications to histone tail amino acids that affect chromatin structure

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4
Q

what are the 3 common epigenic marks

A

histone acetylation
histone methylation
DNA methylation

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5
Q

histone acetylation def

A

decondensation of chromatin . expression.

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6
Q

DNA methylation def

A

specifically CG is the target of the promoter. no expression

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6
Q

histone methylation def

A

condensation of the chromatin. no expression

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7
Q

no expression is what

A

closed. and condensed

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7
Q

expression is what

A

open and not condensed

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8
Q

methylated promoter equals what

A

no expression

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9
Q

no methylation of the promoter equals what

A

active expression

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10
Q

at nuclear scale we can seee what in the nucleas

A

heterochromatin and euchromatin

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11
Q

heterochromation def

A

heavily condensed areas of chromatin “the bad”

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12
Q

euchromation def

A

acetylated, open areas of chromatin. genes are actively expressed. “good”

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13
Q

two types of heterochromation

A

faculative and constitutive

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14
Q

faculative def

A

the hetero CAN be converted to euchromatin

15
Q

constitutive def

A

will ALWAYS remain heterochromatic

16
Q

Epigenic marks are passed on when

A

during DNA replication

17
Q

if a parent cell is methylated , what happens to the daughter cells

A

they must both be methylated as well

18
Q

to get methylated daughter cells, what extra step occurs

A

DNA methyltransferase

19
Q

transgenerational epigenetic inheritance is possible is what

A

many organisms, though not mammals

20
Q

odarent def

A

induces egg laying

21
Q

big picture of transgenerational epigenetic inheritance

A

its a long term phenotypic consequences due to the environmental conditions of a few ancestors that will affect a wide range of generations to come.

22
Q

epigenetic def

A

upon genetics or in addition to genetics

23
promoter leads to wild type or agouti
agouti
24
dosage compensation is necessitate by what
an unequal number of sex chromosomes in different sexes
25
unequal dosage means what on an autosomal locus
there would be 2 x dosage of protein A in males and females
26
unequal dosage means what on x chromosomal locus
there would be 2x dosage of protein B in females but only 1x dosage of protein b in males
27
what does dosage compensation mean
that there would be 1x dosage of B in females, and then seperately there is 1x dosage of B in males.