Slideshow 16 Flashcards
condensation of chromatin leads to what
solenoids
assembly of the nucleosome results in what
histone tails
epigenic marks are what
chemical modifications to histone tail amino acids that affect chromatin structure
what are the 3 common epigenic marks
histone acetylation
histone methylation
DNA methylation
histone acetylation def
decondensation of chromatin . expression.
DNA methylation def
specifically CG is the target of the promoter. no expression
histone methylation def
condensation of the chromatin. no expression
no expression is what
closed. and condensed
expression is what
open and not condensed
methylated promoter equals what
no expression
no methylation of the promoter equals what
active expression
at nuclear scale we can seee what in the nucleas
heterochromatin and euchromatin
heterochromation def
heavily condensed areas of chromatin “the bad”
euchromation def
acetylated, open areas of chromatin. genes are actively expressed. “good”
two types of heterochromation
faculative and constitutive
faculative def
the hetero CAN be converted to euchromatin
constitutive def
will ALWAYS remain heterochromatic
Epigenic marks are passed on when
during DNA replication
if a parent cell is methylated , what happens to the daughter cells
they must both be methylated as well
to get methylated daughter cells, what extra step occurs
DNA methyltransferase
transgenerational epigenetic inheritance is possible is what
many organisms, though not mammals
odarent def
induces egg laying
big picture of transgenerational epigenetic inheritance
its a long term phenotypic consequences due to the environmental conditions of a few ancestors that will affect a wide range of generations to come.
epigenetic def
upon genetics or in addition to genetics