Slideshow 16 Flashcards

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1
Q

condensation of chromatin leads to what

A

solenoids

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2
Q

assembly of the nucleosome results in what

A

histone tails

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3
Q

epigenic marks are what

A

chemical modifications to histone tail amino acids that affect chromatin structure

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4
Q

what are the 3 common epigenic marks

A

histone acetylation
histone methylation
DNA methylation

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5
Q

histone acetylation def

A

decondensation of chromatin . expression.

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6
Q

DNA methylation def

A

specifically CG is the target of the promoter. no expression

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6
Q

histone methylation def

A

condensation of the chromatin. no expression

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7
Q

no expression is what

A

closed. and condensed

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7
Q

expression is what

A

open and not condensed

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8
Q

methylated promoter equals what

A

no expression

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9
Q

no methylation of the promoter equals what

A

active expression

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10
Q

at nuclear scale we can seee what in the nucleas

A

heterochromatin and euchromatin

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11
Q

heterochromation def

A

heavily condensed areas of chromatin “the bad”

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12
Q

euchromation def

A

acetylated, open areas of chromatin. genes are actively expressed. “good”

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13
Q

two types of heterochromation

A

faculative and constitutive

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14
Q

faculative def

A

the hetero CAN be converted to euchromatin

15
Q

constitutive def

A

will ALWAYS remain heterochromatic

16
Q

Epigenic marks are passed on when

A

during DNA replication

17
Q

if a parent cell is methylated , what happens to the daughter cells

A

they must both be methylated as well

18
Q

to get methylated daughter cells, what extra step occurs

A

DNA methyltransferase

19
Q

transgenerational epigenetic inheritance is possible is what

A

many organisms, though not mammals

20
Q

odarent def

A

induces egg laying

21
Q

big picture of transgenerational epigenetic inheritance

A

its a long term phenotypic consequences due to the environmental conditions of a few ancestors that will affect a wide range of generations to come.

22
Q

epigenetic def

A

upon genetics or in addition to genetics

23
Q

promoter leads to wild type or agouti

A

agouti

24
Q

dosage compensation is necessitate by what

A

an unequal number of sex chromosomes in different sexes

25
Q

unequal dosage means what on an autosomal locus

A

there would be 2 x dosage of protein A in males and females

26
Q

unequal dosage means what on x chromosomal locus

A

there would be 2x dosage of protein B in females but only 1x dosage of protein b in males

27
Q

what does dosage compensation mean

A

that there would be 1x dosage of B in females, and then seperately there is 1x dosage of B in males.