Slideshow 13 Flashcards
What is a more radical change
translation
do codes overlap
no
Ribosomes with large and small subunits, are what
aggregates of rRNAs and proteins
Prokaryotic initiation of translation uses what sequence
the shine-dalgarno sequence
what does the shine dalgarno sequence do
its a sequence at the 5’ end of the mRNA upstream of the start codon, which pairs wirh rRNA and positions the mRNA properly
Initiation Factor proteins in prokaryotes
A U G
what is the eukaryotic translation initiation factor
eIF
EF-Tu def
elongation factor, brings next amnoacyl tRNA to the A site
EF-G def
moves assembly to expose next codon
Peptidyl transferase def
catalyzes peptide bond formation
is termination of translation similar in pro and euk
yes
release factor def
a protein that pairs a tripeptide rather than an anticodon with the stop codon; its bonding causes dissociation of the whole assembly
tRNAs def
work as adapters or translators to connect that language of nucleic acid and amino acids
what two things need the tRNA
protein and RNA
Acceptor end def
binds amino acid
anticodon def
binds a complementary and anitparallel codon
canonical base pairing def
A=T C=- G A=U
Wobble Base Pair
I with either A/C/U
what is a 2 degree. or secondary structure
it went through foldingq
Aminoacyl tRNA synthetases def
plays a critical role in translation : charging tRNAs with the correct amino acid
active sites of a synthetase are what
tRNA based on its anticodon
amino acid
what is the purpose for wobble base pairing
to reduce the number of unique tRNAs and aminoacyl tRNA synthetases
where is teh wobble base pair always
on the 3’ most nucleotide fo the codon
