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Jason's Intersystem Block > Skin&Tissue Infections > Flashcards

Skin&Tissue Infections Flashcards

1
Q

skin microbiota mainly?

A

bacteria yeasts

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2
Q

microbiota gram -ve:

A

Pseudomonas

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3
Q

Gram +ve skin microbiota:

A
  1. Staph epidermidis
  2. Staph aureus
  3. diptheroids
  4. streptococci
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4
Q

‘rose spots’ indicated?

A

enteric fever

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5
Q

petechiae in?

A

septicaemia

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6
Q

what is bacteria fasciitis?

A

necrotising

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7
Q

what type of infection is impetigo/cellulitis?

A

spreading

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8
Q

what type of infection is folliculitis/abscess?

A

localised

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9
Q

folliculitis is infections of?

A

hair follicle from blockage

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10
Q

what is a furuncle?

A

boil/abscess

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11
Q

cause of folliculitis usually?

A

Staph Aureus

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12
Q

where usually get furunculosis?

A

back of neck or sweaty areas

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13
Q

staph saprophyticus where?

A

UTI

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14
Q

Body’s primary defence against Staph Aureus ?

A

innate immunity

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15
Q

How does Staph Aureus overcome neutrophils?

A

vast array of virulence factors

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16
Q

what is Panton-Valentine leukocidin?

A

secreted by Staph Aureus survives neutrophils

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17
Q

what staph is good at making biofilm?

A

staph epidermadis

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18
Q

Staph Aureus 90% resistant to? use what?

A

penicillin, use methicillin unless MRSA then use Vancomycin

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19
Q

CA-MRSA or hospital MRSA more virulent?

A

CA-MRSA more virulent

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20
Q

what characterizes Impetigo?

A

bullous, crusted, pustular lesions

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21
Q

what 2 things cause impetigo?

A

staph aureus

Group A B-haemolytic strep/GAS/Strep Pyogenes

22
Q

Bullous impetigo caused by?

A

Staph Aureus

23
Q

what is erysipelas?

A

rapidly spreading erythematous infection with fell defined borders, pain+fever

24
Q

difference between cellulitis and erysipelas?

A

cellulitis involved subsutaneous fat

25
Q

cellulitis and erysipelas caused by?

A

GAS/Strep Pyogenes/group A B-haemolytic strep

26
Q

Group A B-haemolytic strep AKA?

A

strep pyogenes

27
Q

Cellulitis can be caused by more than Strep pyogenes: name 2:

A

Staph Aureus

Vibrio species

28
Q

Staph aureus usually causes what kind of impetigo?

29
Q

strep pyogenes AKA?

A

Group A B-haemolytic strep

30
Q

when get anaerobic cellulitis?

A

devitalised tissue

31
Q

Necrotising fasciitis/Gangrene most common cause? 2

A

Group A B-haemolytic strep/strep pyogenes

Clostridium perfringens

32
Q

B-haemolysis colour on agar?

33
Q

a-haemolysis colour on agar?

34
Q

Group A Strep M-protein numbers and virulence?

A

lower numbers = more virulent than higher numbers

35
Q

what are NETS?, how does Group A B-haemolytic strep evade?

A

NETS = neutrophil traps

evades via DNAase

36
Q

3 ways Group A B-haemolytic strep cause damage?

A
  1. direct via enzymes and toxins
  2. superantigens (ToxSSyn)
  3. autoimmunity
37
Q

clostridia are gram what? what shape?

A

gram +ve Rods

38
Q

clostridia usually come from where?

A

environment

39
Q

clostridia aerobic or anaerobic?

40
Q

2 clostridia most common?

A

C. tetani

C. perfringens

41
Q

where does clostridia spores like to germinate/replicate?

A

anaerobic devitalized tissue

42
Q

clostridia in litmus milk?

A

blasted apart denatured milk proteins

43
Q

2 situations when Pseudomonas can infect?

A

diabetic foot ulcer

Burns

44
Q

2 kinds of fungi that cause skin/soft tissue infection?

A
  1. dermatophytes

2. Yeasts (Candida)

45
Q

what is chronic mucocutaneous candidiasis?

A

candida from primary immunodeficiency

46
Q

arthropods eg?

A

insects, ticks, mites

47
Q

when is crusted scabies happen?

A

elderly, immunosuppressed

48
Q

two kinds of Herpes Simplex virus apperance?

A
  1. oral herpes

2. eczema herpeticum

49
Q

2 main viruses causing skin infections?

A

Varicella

HSV

50
Q

why impregnate with silver?

A

suppress pseudomonas

51
Q

how to treat abcess?

A

drain

antibiotic

Jason's Intersystem Block (19 decks)

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