Skin Flashcards
what is panniculitis?
inflamm of subcutaneous tissue
what is adnexal?
sweat glands, hair, sebaceous glands
where are sweat glands in the skin?
dermis and hypodermis
where are hair follicle in the skin?
dermis and hypodermis
5 layers of epidermis?
Stratum: Basale Spinosum granulosum lucidum corneum
what does the stratum spinosum look like ihstologically?
intercelullar bridges with desmosomal junctions
why is dermo-epidermal junction tortuous?
increase surface area to minimize sloughing of epidermis during shear forces
what is dermal papilla
outcropping of dermis into epidermis
main cells in the epidermis?
keratinocytes
what is epidermal rete ridge?
outcropping of epidermis into dermis
what attaches from keratinocyte to basement membrane?
hemi-desmosome
how long for a basal cell epidermal life cycle?
60 days
ratio of melanocytes to keratinocytes
1:10
melanocyte structure? where is it?
between basal cells
large cytoplasmic processes extend up between keratinocytes
purpose of melanocytes?
make melanin to protect keratinocytes’ nuclei against UV
3 things determine skin colour
genetics
sun exposure
blood flow
what are Langerhans cells of the epidermis?
antigen presenting cells active in contact dermatitis and other neoplastic lesions
what kind of cells are Merkel Cells ?
neuro-endocrine cells
active in touch
what are the 2 main layers of dermis? collagen?
- Papillary - fine collagen with elastic
2. reticular - coarse collagen
what do papillary and reticular dermis both contain?
macrophages APCs
what surrounds sweat glands?
myoepithelial cells to contract
muscles around hair called?
erector pili
sebaceous glands empty into?
hair follicles
what kind of sweat glands in armpits?
apocrine sweat glands
how to temp regulate in skin?
change the arteriovenous anatomosis levels
where are the free nerve endings in skin?
epidermis
what kid of skin in hands and feet?
thick skin glaberous
more keratin, no hair follicles, yes sweat glands
wound a few weeks old has?
granulation tissue
healing by primary intention?
less scar
less granulation tissue
ends closer together
healing by secondary intention? time? susceptibility?
takes longer
susceptible to infection and dehydration
3 phases of healing?
inflamm
proliferation
maturation
superficial burns affects?
epidermis only
partial thikness affects?
epidermis + dermis varying
full thickness burn affects?
full epidermis, dermis and variable subutaneous
surgical incisions should be made where?
along cleavage lines to minimize scarring
keloid scar is?
excessive collagen formation