Obstetric Pharmacology

Question 1

pharmacokinetics sequence acronym?

Answer 1

ADME
Distribution: through placenta
Excretion: mother + fetus

Question 2

what is the Function of placenta acronym?

Answer 2

TIME
T-transport
I-immunological
M - metabolic
E - endocrine

Question 3

1 cause of maternal mortality?

Answer 3

cardiac disease

Question 4

1 cause of maternal morbidity?

Answer 4

obstetric haemorrhage

Question 5

risk of blood lose for all women?

Answer 5

1.8%

Question 6

3 goals of obstetric haemorrhage?

Answer 6

1. control bleeding
2. restore O2 carring
3. maintain tissue perfusion

Question 7

2 important drugs in obstetric hemorrhage?

Answer 7

Oxytocin

Ergometrine

Question 8

2 important fluids in obstetric hemorrhage?

Answer 8

0.9 isotonic NaCl

blood transfusion

Question 9

what is ROSE scan?

Answer 9

Rapid Obsteric screening echocardiography scan

Question 10

Preeclampsia usually started when?

Answer 10

> 20 weeks to 3/12 post-partum

Question 11

Preeclampsia affects how many % preg women

Answer 11

5-8%

Question 12

gestational hypertension is called?

Answer 12

uncomplicated hypertension

Question 13

what kind of hypertension is Preeclampsia ?

Answer 13

complicated hypertension

Question 14

top two causes of death due to hypertension in pregnancy?

Answer 14

cerebral complications

cardioresp failure

Question 15

severe Preeclampsia BP?

Answer 15

SBP >180mmHg

Question 16

How to prevent seizures of severe Preeclampsia ?

Answer 16

MgSO4

Question 17

Preeclampsia hypertension treatment drug?

Answer 17

Labetalol

Non-celective B-adrenoceptor antagonist and competitive a1-adrenoceptor antagonist