Skin Pathology V

Question 1

verrucae

Answer 1

warts

caused by HPV

cutaneous - 2/4
anogenital - 6/11

gray white to tan 0.1 to 1cm papules

Question 2

condyloma plantaris

Answer 2

wart on foot

Question 3

condyloma palmis

Answer 3

wart on palm of hand

Question 4

condyloma acuminatum

Answer 4

anogenital cauliflower like warts

1-4 cm

Question 5

poxvirus

Answer 5

causes molluscum contagiousum
-transmission - direct contact

young children and adults

face, trunk, anogenital region

Question 6

acne vulgaris

Answer 6

teenage zits
-chronic smoldering infection of hair follicle

lipase producing propionibacterium acne

Question 7

cure of acne vulgaris

Answer 7

isotretinoin - retin-A + antibiotic

retin A - alters chemical composition of sebum of hair follicle

antibiotic - minocycline (tetracycline to hair shaft)

Question 8

impetigo

Answer 8

superficial infection of skin
-highly contagious

hands and face
-contagiosa and bullosa forms

staph aureus**

Question 9

staph aureus

Answer 9

toxin cleaves desmoglein 1 - leads to impetigo

antibacterial soap tx

Question 10

dermatophyte fungal species

Answer 10

superfical fungal infection

in stratum corneum
-thrive in keratin of cornified layer

Question 11

predisposition for skin infection by fungus

Answer 11

high moister
lack of sunlight exposure
increased temperature

Question 12

superficial fungal infection of skin

Answer 12

tinea

Question 13

fungal infection children scalp

Answer 13

tinea capitis

Question 14

ringworm

Answer 14

tinea corporis

Question 15

inguinal skin genital fungal infection, obese men in hot weather

Answer 15

tinea cruriis

Question 16

athletes foot

Answer 16

tinea pedis

Question 17

bear fungal infection

Answer 17

tinea barbae

Question 18

nail bed fungal infection

Answer 18

onychomycosis

Question 19

malassezia furfur

Answer 19

yeast

-causes tinea versicolor

Question 20

brown recluse

Answer 20

direct toxin effect on skin

Question 21

mosquito

Answer 21

malaria
west nile
dengue

Question 22

ticks

Answer 22

lyme disease

rocky mtn spotted fever

Question 23

ichthyosis

Answer 23

hyperkeratosis
-resembles fish scales

X-linked, auto rec, and auto dom forms

Question 24

epidermilysis bullosa

Answer 24

genetic abnormality in structural protein
-massive bulla

simplex - keratin 14 or 5 mutation
junction - lamina lucida defect
dystrophic - anchoring fibril defect
mixed - multi regions

Question 25

porphyria

Answer 25

auto dom defect in heme synthesis

urticaria and subepidermal vesicles with sun exposure

Question 26

acute neurovisceral with GI and neural sx

Answer 26

acute intermittent

• porphobilinogen deaminase
• aminolevulinic acid dehydratase deficient

Question 27

acute neurovisceral with cutaneous problems

Answer 27

variegate - protoporphyrogen oxidase

hereditary coproporphyria - coproporphyrinogen oxidase

Question 28

non-acute - cutaneous with light induced lesions

Answer 28

congeintal erythropoetic - uroporphyrinogen III synthase

erythropoetic - erythrohepatic protoporphyria - ferrochelatase

X-linked protoporphyria - overactive amino levulinic aid synthase

cutanea tarda - uruporphyrogen III decarboxylase

• with hypertrichosis
• urine dark or red with light exposure