Dermatology in the Office Flashcards
types of eczematoid dermatitis
atopic
contact
stasis
shingles across dermatome
herpes zoster
IgA bullous dermatitis
drugs
marker for malignancy
seborrheic keratosis
lesions stuck on - signs of leser trelat
multiple seborrheic keratosis
underlying GI malignancy
multiple melanoma mets
to liver
staphylococcus
forms biofilm blocks sweat glands
TLR2 - activated in areas where blocked sweat duct
tx of eczema
steroids and oil based moisturizer
job syndrome
hyper IgE
eczema plus a neutrophil problem
decreased IL8**
child hx staphylococcal abscess, pneumonia, high IgE, high eosinophils, rash
primary problem?
phagocytic dysfunction
thrombocytopenia and eczema
wiskott aldrich
nervous scratching
lichen simplex chronicus
dry itching lesion in winter
nummular eczema
coin shaped - from washing too much
silver sheen lesion
psoriasis
flare up of psoriasis
stop steroid use
flare up of psoriasis
may be marker for HIV
breakout with contact
koebner phenomenon
ex/ poison ivy
associated with MI, athersclerosis, metabolic syndrome, NAFLD, IBD, depression
psoriasis
suppressed Treg cells and hyperactive Th1 and Th17 cells
nail pits and oil spots
psoriasis
ring worm diagnosis
KOH prep
proximal superficial onychomycosis
suggest of AIDS
should normally see fungal infection of distal nail, not proximal
woods yellow fluorescence
malassezia fur fur - tinea versicolor
worsening of tinea versicolor
cushings, malnutrition, and immunosuppression
steroid acne
same condition of malassezia folliculitis
proliferation of malassexia yeast - pitysporum
pink fluorescence under woods
corynbacterium
green under woods
cat ringworm
-microsporum canis
exfoliative dermatitis tx
need fluids - due to dehydration
women BCP, hep C, elevated ALT, increased temporal hair growth, polychlorinated aromatic hydrocarbon exposure
HUD deficiency
porphyria pathway defect
red on woods
urine with porphyria
caterpillar bodies
uroporphyrinogen deposition
b/l pneumonia and bullous myringitis
mycoplasma infection
target lesion
erythema multiforme
due to drugs
SNS and TEN
steven johnson syndrome
toxic epidermial mecrolysis
cytotoxic T cells to 2x oral membranes
SNS and TEN
causes of SJS/TEN
west - oxicam NSAIDs, sulfas
east - carbamazepine, allopurinol
carbamazepine
cause of SJS/TEN in east
HLA B1502 and HLA B5801
susceptible to SJS/TEN
B1502 - carbamazepine
B5801 - allopurinol
30% of body involved with fever, conjunctivitis, pharyngitis, GI ulcers, tracheal erosions, pancytopeni, and sepsis
TEN - after >30% of body covered
sharp demarcation
strep infection
St. anthonys fire if on face
associated with colon, gyn, lymphoreticular malignancy
clostridium septicum
rash after spa
pseudomonas
eosinophilic folliculitis
HIV
staph folliculitis
itches
tattoo artist, complains of spider bite
MRSA infection
comedones
acne vulgaris - clogged hair follicles
impetigo concern
post strep GN
acne bug
propionibacterium acnes
tenalgiectasia and erythema
rosascea
rhinophyma
rosascea enlarges nose
complication of rosascea
can go blind - corneal melting
also associated with parkinsons
parkinsons association
rosascea and seborrheic dermatitis
demodex mite
rosascea
parkinsons
TRAMP2S3
S - swallowing, seborrheic dermatitis, slow speech
tremor asked to smile
get seborrheic dermatitis
-with parkinsons
bug in seborrheic dermatitis
malassezia furfur
-yeast
condyloma acumanatum
HPV
condyloma latum
syphilis
lyme disease
ioxides scapularis - deer tick
herpes zoster complication
involve eye
-refer to ophthalmology
stages of lymes
1 - targetoid lesion - flu symptoms
2 - dissemination - heart block bells palsy**, migratory arthralgias
3 - late joints and CNS/PNS - oligoarthritis, encephalitis
pox virus
molluscum contagiosum
umbilicated lesions
long incubation, in HS wrestlers, umbilicated lesion
molluscum contagiosum - pox virus
HHV8
kaposi sarcoma
with HIV - CD4<500
christmas tree distribution
pityriasis rosea
-herald patch where started
complication with pityriasis rosea
spontaneous abortion in pregnant
and looks like syphilis
physician intubated without gloves
herpes
-herpetic whitlow
parvovirus B19
fifths disease
mother with iron defiency anemia - may develop aplastic anemia
ssDNA virus
petechia on soft palate
forschheimer sign
associated with rubella
blueberry muffin baby
rubella
-togairus - ssRNA
-rash, headache, polyarthritis, malaise, lymphadenopathy, dermal hematopoiesis, deafblindness
rash and bluish white spots in mouth, fever, conjunctivitis, coryza, cough
rubeola
measles
koplik spots
measles
paramyxovirus
-ssRNA
seven year itch
scabies - mites
vagabonds disease
crabs - louse
cocaine and cutaneous necrosis
levamisole
elevations on nails
beaus line
marker for acute illness
clubbing of fingers
periosteal new bone formation
lung cancer, cardiac issues
PDF, VEGF, and PGE2
osteoblast proliferation
subperiosteal new bone formation
DRESS
drug rash with eosinophilia and systemic disorder
2-6 weeks after start new med
progression to acral edema and pinpoint pustules and desquamation
IL5 disease**
tuberculin rxn
macrophage activation
type IVa gell combs
poison ivy
contact dermatitis
macrophage activation
type IVa gell combs
B cell lymphoma with angioedema
Abs against C1 esterase - leads to deficiency
cause of angioedema
bradykinin
screen with C4
bee sting rxn
IgE type 1
anaphylaxis
IgE mast cell degranulation
CRH
stress released
-can cause hives
wheals that lead to ecchymosis
urticarial vasculitis
if urticaria >24 hours - chronic
T cell lymphoma
mycosis fungoides
stages of mycosis fungoides
patch
plaque
tumor
problem - invades organs
vitiligo
HLA B27 association
autoimmune - check adrenal and thyroid
subacute cutaneous lupus erythematous
photosensitive
-RO/SSA Abs
daughter with heart block
RO/SSA Abs
SCLE
erythema nodosum
streptococcus
celiac association
dermatitis herpetiformis
vesicular lesions - IgA deposits in skin
nikolskys sign
rub off skin
seen with pemphigus
granuloma annulare expect what
hyperlipidemia
reddish bumps on skin in circle or ring shape