skin cancer and homeostatic imbalances Flashcards
what is skin cancer?
when basale cells do mitosis rapidly due to overexposure of UV rays
what is basal cell carcinoma?
most common skin cancer, when basal cells cannot form keratin
where does the cancer occur in basal cell carcinoma?
dermis and subcutaneous layer in areas exposed to the sun
what is the treatment for basal cell carcinoma?
surgical removal
where does squamous cell carcinoma develop?
in the stratum spinosum layer
what are the 4 places squamous cell carcinoma is found?
- lips
- back of hands
- scalp
- ears
what is the regular treatment for squamous cell carcinoma and what is the treatment when it gets very serious?
surgical removal for regular and radiation if it invades the lymph nodes
where is malignant melanoma formed?
in melanocytes
what is malignant melanoma?
most deadly skin cancer, can break off lymph vessels and blood vessels
what are the 4 treatments for malignant melanoma?
- surgical removal
- immunotherapy
- chemotherapy
- radiation therapy
what does the ABCDE rule in identifying skin cancer?
A - Asymmetry
B - Border irregularity
C - Color
D - Diameter
E - Evolving
what is the A for in the ABCDE rule of skin cancer?
when you split the skin cancer in half, does it look the same on both sides
what is the B for in the ABCDE rule of skin cancer?
is the shape of the skin cancer round or irregular in shape
what is the C for in the ABCDE rule of skin cancer?
is the skin cancer black or 2-toned
what is the D for in the ABCDE rule of skin cancer?
is the diameter of the skin cancer larger than 6 mm
what is the E for in the ABCDE rule of skin cancer?
does the skin cancer change in shape or size, does it bleed or itch
between what times should someone not be in the sun?
between 10 AM and 4 PM
what is another name for decubitus ulcers?
bedsores
what is bedsores?
skin ulcer caused by the restriction of blood supply which is due to prolonged pressure in one area
what type of homeostatic imbalance is when poorly oxygenated blood causing skin to look blue?
cyanosis
what is acne?
infection of sebaceous glands
what is a whitehead?
sebum blocking sebaceous glands
what is a blackhead?
when a whitehead becomes oxidized which makes it change color
what is sebum?
an oily substance to keep skin moisturized
what is another name for seborrhea?
cradle cap
what is a cradle cap?
on the scalp of a baby, sebum buildup causes it to become yellow and crusty
what is cold sores?
fluid filled blisters around mouth and genital areas
what causes cold sores?
herpes simplex virus
what happens when someone gets contact dermititis?
itchiness, redness, and swelling of skin
what causes contact dermatitis?
exposure to chemicals (like poison ivy, oak)
what is a lesion?
damage to the tissue caused by trauma or disease
what causes impetigo?
bacteria
what is impetigo?
pink, water filled lesions which are around mouth & nose
what causes psoriasis?
overproduction of skin cells
what is the result of psoriasis?
dry, itchy, red patches
what are the 3 pigments that contribute to skin color?
- melanin
- carotene
- hemoglobin
what is the color range for melanin?
yellow, red-brown, black
what is melanin responsible for and what does it cause?
responsible for the tanning of the skin, causing the more melanin you have, the darker you are
how does the sun affect melanocytes?
it worsens melanin buildup
what is the color range of carotene?
yellow, orange
what are the 3 places carotene is found?
- carrots
- palms of hands
- soles of feet
what vitamin is in carotene?
vitamin A
what is carotene?
pigment found in plants to give it its color
what are the 6 colors of hemoglobin?
- pale
- yellow
- blue
- pink
- bronze
- redness
what hemoglobin is pale what does it mean?
pale color is caused by lack of blood
what hemoglobin is yellow what does it mean?
caused by buildup of bile in the blood, also known as Jaundice
what hemoglobin is blue what does it mean?
also known as cyanosis, is the lack of oxygen
what hemoglobin is pink what does it mean?
it has a normal hue
what hemoglobin is bronze what does it mean?
can be Addison’s disease which has a metallic appearance
what hemoglobin is redness what does it mean?
can be erytheme, blushing, inflammation, hypertension
what hemoglobin is dark purple, green, yellow in color and what is it?
bruises is when blood escapes & clots tissue space
what is the hair, or pili made of?
keratin
what is the function of the shaft of the hair?
shoots hair out from the skin
what is the root of the hair for?
it is in the skin to show what type of hair it is (curly or straight)
what is the function of the hair matrix for?
to grow new hair because it is rich in blood supply
what 5 things are in the hair follicle?
- hair root
- nerve endings
- papilla, or the capillaries
- arrector pili which raises hair
- melanocytes give hair color
what is the fine body hair on children and females called?
fine vellus
what is terminal hair and how does it grow?
scalp hair and eyebrows grow in response to sex hormones (meaning more testorone, the more terminal hair)
what is alopecia?
hair loss, new hairs don’t replace old hairs as quickly
what is male pattern baldness?
a genetic and sex-influenced condition
what are nails made of?
hard keratin
what is the nail matrix for?
for new nail growth
what is another term for eponychium?
cuticle
what is the function of the cuticle?
to protect nail matrix
what is the function of the hyponychium?
attaches to underlying tissue/nail bed
what is another term for sudiforous glands?
sweat glands
where are sweat glands located?
entire body except for nipples and external genitalia
how many sweat glands per person?
2.5 million per person
what are the 3 types of sweat glands?
- eccrine
- apocrine
- sebaceous
what are the 3 places eccrine sweat gland found?
- palms of hands
- soles of feet
- forehead
what is the purpose of the eccrine sweat glands?
for temp regulation
what kind of tissue is apocrine sweat gland?
stratified cuboidal tissue
what are the 2 locations apocrine sweat glands are found?
- axillary (armpit)
- genital areas
what is the purpose of apocrine sweat glands?
to make body odor made of decomposed fats and proteins
what is another term for sebaceous glands?
oil glands
where is sebaceous glands located?
all over body except palms of hands and soles of feet
what does sebaceous glands secrete?
sebum (oil)
what are the 2 functions of sebaceous glands?
- to smooth & soften hair + skin
- slows water loss
what is a type of nerve ending?
cutaneous sensory receptors
what do cutaneous sensory receptors do?
respond to stimuli
what are the 5 types of cutaneous sensory receptors?
- meissner’s corpuscles
- pacinian receptors
- root hair plexuses
- bare nerve endings
- merkel discs
what is meissner’s corpuscles?
in the superficial of the dermis, can sense light touch
what is pacinian receptors?
in the deep of the dermis, detects pressure
what does bare nerve endings do?
sense cold, heat
where are merkel discs located and what is its function?
in basal layer, for fine special separation