Skeletal System Disorders Flashcards
bone consists of:
organic matrix with inorganic salts primarily calcium and phosphorous
outer fibrous membrane of bone containing a network of blood vessels transporting nutrients
periosteum
main shaft-like portion of bone
diaphysis
ends of bone
epiphysis
hollow, tube like structure within the diaphysis that holds marrow
medullary cavity
inner membrane of the bone
endosteum
bone consits of 2 highly specialized connective tissues:
bone and cartilage
dense bone within the haversian system
compact bone
name some compact bones
femur, tibia, carpal and tarsal bones
spongy web like arrangement of marrow filled spaces separated by trabeculae
cancellous bone
name some cancellous bones
facial bones, vertebral bodies
what type of cartilage is bone composed of
hyaline cartilage
purpose of osteoclasts
enlarge the medullary cavity
purpose of osteoblasts
form new bone on periosteum
bones that grow in size by the addition of osseous tissue to their outer surfaces
flat bones
at what age do bones begin to thin out
40
numbness in the upper extremities could be caused by which bone disorder
transitional vertebrae
transverse processes forming joints with the sacrum, leads to degenerative change in opposite hip
transitional vertebrae
posterior defect resulting in failure of the posterior elements to fuse properly
spina bifida
“marble bone” bone dysplasia resulting from a failure of resorption mechanism of calcified cartilage (increase in bone density)
osteopetrosis
insufficient mineralization of adult skeleton, resulting from excessive osteoid formation
osteomalacia
systemic infant disease caused by a deficiency of vitamin D or lack of exposure to sunlight
Rickets
increased levels of uric acid leading to a deposition of uric acid crystals in joints, cartilage, and kidneys cause by a malfunction of purine metabolism
Gout
bone disease categorized by “rat bite” sign
Gout
destruction of bone followed by a reparative process resulting in weakened, deformed and thickened bony structures
Paget’s Disease
bone disease categorized by mottled appearance or “cotton ball effect”
Paget’s Disease
benign projection of bone with a cartilaginous cap that arises in teen / childhood years
Osteochondroma
slow growing benign cartilaginous tumor arising in the medullary canal
enchondroma
tumor that arises at the distal end of the femur or proximal tibia of young adults after epiphyseal closure
giant cell tumor
tumor that often arises in the outer table of the skull, paranasal sinuses, and the mandible
osteoma
small round tumor surrounded by a large area of sclerotic tissue and cortical thickening, usually in femur or tibia
osteoid osteoma
fluid filled cyst with a wall of fibrous tissue
simple bone cyst
blood filled arteriovenous communications usually occurring in long bones
aneurysmal bone cyst
solitary, sharply demarcated areas of dense compact bone that occur most commonly in pelvis and upper femur
bone islands
appears as a mixed destructive and sclerotic lesion associated with a soft tissue mass, irregular periosteal reaction and classic “sunburst” pattern
Osteogenic sarcoma
often originates from cartilage or preexisting cartilaginous lesion, appears as granular calcifications within a mass
Chondrosarcoma
ill-defined areas of bone destruction that involves central portion of the shaft and associated with periosteal reaction parallel to the shaft
Ewing’s Sarcoma
widespread malignancy of plasma cells associated with bone destruction, appears as punched out osteolytic lesions scattered throughout the skeletal system
multiple myeloma
most common malignant bone tumors spreading by means of blood stream or lymphatic vessels or by direct extension
bone metastases