Endocrine System Flashcards
biochemical communication network of small glands regulating a broad range of vital body activities
endocrine system purpose
Name endocrine glands
pituitary, adrenal, thyroid, parathyroid
inadequate secretion of hormones
hypoactive endocrine
excess production of hormones
hyperactive endocrine
acts as a thermostat, when a sufficient amount of hormone is detected in blood, production stops and when levels drop new hormones are released
negative feedback mechanism
the production of two different hormones working opposite to one another such as insulin releasing to reduce blood sugar levels and glucagon released to raise glucose levels
hormone balance
released to reduce blood sugar levels
insulin
released to raise blood glucose levels
glucagon
sits on top of the kidneys, consists of a cortex and inner medulla
adrenal glands
what do adrenal glands secrete
mineralocotoids, glucosteroids, adrogens
regulates salt and water balance by controlling the retention of sodium and excretion of the potassium
mineralocoroids (aldosterone)
regulates carbohydrate metabolism
glucosteroids (cortisone)
masculinize the body, retains amino acids and increases protein synthesis
adrogens (sex hormones)
excess production of glucosteroid hormones mobilizing lipids and increases lipids in blood levels
Cushings syndrome
characterized by obesity of trunk, moon shaped face, and large fat pad behind the shoulders (Buffalo bump)
Cushings syndrome
attributed to generalized bilateral hyperplasia of the adrenal cortex or the result of a functional adrenal or non adrenal tumor
Cushings syndrome
manifests as enlargement of the adrenal gland, produces changes in multiple systems such as diffuse osteoporosis, collapse of vertebral bodies, spontaneous fractures, and septic necrosis of the head of the femur or humerus
Cushings syndrome
an overproduction of mineralocortcoid hormones produced by the most superficial layer of the adrenal cortex that causes retention of sodium and water and loss of potassium in the urine
aldosteronism
results in hypertension, muscular weakness or paralysis, and excessive thirst (polydipsia)
aldosteronism
attributable to an adrenocortical ademona (Conn’s syndrome), bilateral hyperplasia of the superficial cortical layer, renin secreting tumors, renal artery stenosis, malignant hypertension or bilateral chronic renal disease
aldosteronism
results from the excessive secretion of androgenically active substance of the adrenal gland, also known as adrenal virilism
adrenogenital syndrome
excessive androgenic hormones causes continuous ACTH stimulation and bilateral hyperplasia, accelerated maturation and premature epiphyseal fusion leading to dwarfism
adrenogenital syndrome
adrenal insufficiency characterized by anorexia, fatigue, weakness, weight loss, and increased melanin pigmentation
chronic hypoadrenalism
adrenal insufficiency characterized by hypotension, rapid pulse, vomiting and diarrhea
acute hypoadrenalism
primary adrenocortical insufficiency that results from progressive cortical destruction, must include 90% of the glands before clinical signs appear
Addison’s disease
about half of adrenal carcinomas cause
cushings syndrome, virilization, feminization, or aldosteronism
modality used to demonstrate complex tumors that may be difficult to separate from upper pole of the kidney
ultrasound
radiographically categorized as metastatis causing downward displacement of the kidney with flattening of the upper pole
adrenal metastasis
a tumor arising from the adrenal medulla, produces an excess of vasopressor substances (epinephrine and norepinephrine), can cause an uncommon form of hypertension
phenochromocytoma
highly malignant tumor of adrenal medulla origin, second most common malignancy
neuroblastoma
master gland, size of a pea, suspended from the base of the brain by a slender stalk (infundiblum) and sits in sella turcica
pituitary gland