skeletal system Flashcards
sesamoid bones 1. shape 2. begin as what 3. form where and when
- seed-shaped 2. start as bone spurs 3. form w/in joints throughout life
articular cartilage 1. location 2. made of what
- surrounds the ends of long bones 2. made of hyaline cartilage
periosteum
membrane that covers all bones
endosteum
lining of medullary cavity
3 bone cell types
- osteoblasts 2. osteocytes 3. osteoclasts
osteoblasts
immature bone cells that make new bone tissue (grow and repair bone)
osteocytes
mature osteoblast that are trapped in the bone matrix and maintain it
osteoclasts 1. break down what 2 things 2. by what means
- break down bone tissue and other types of connective tissue 2. by releasing calcium from bone into blood
osteons
structural units of compact bone tissue
central canal 1. location 2. three contents
- cavity running down the middle of osteon 2. blood vessels, nerves, lymphatic vessels
lamellae
concentric rings of bone tissue matrix around central canal
lacunae
spaces between lamellae each containing an osteocyte
canaliculi
tiny canals connecting neighboring lacunae
bone tissue matrix 1. ground substance and it’s affects 2. protein fibers and their affect
- calcium crystals which make bones hard and resistant to compression 2. collagen protein fibers which make bones bendable but resistant to stretching
how long bones grow in length on the epiphysis side of epiphyseal plate (something constantly dividing)
cartilage cells are constantly dividing and making new cartilage which lengthens the diaphysis
how long bones grow in length on diaphysis side of epiphyseal plate (remove something from where and replace w/ what)
osteoclasts and osteoblasts remove the old cartilage of the epiphyseal plate and replace it with spongy bone tissue
how long bones grow in width externally
cells in periosteum form new osteoblasts which form osteocytes (new compact bone)
how long bones grow in width internally
endosteum forms osteoclasts which break down wall of medullary causing it to expand
how non-long bones grow larger externally
cells in periosteum form new osteoblasts which form osteocytes (new compact bone)
how non-long bones grow larger internally
endosteum forms osteoclasts and osteoblasts which replace compact bone tissue with spongy bone tissue
3 hormones that control bone growth
- human growth hormone HGH 2. testosterone 3. estrogen
3 steps of how the epiphyseal plate turns into the epiphyseal line
- testosterone/estrogen reach adult levels which stimulates the epiphyseal plate to close 2. the cartilage cells die 3. the plate is converted to compact bone which forms the line
pituitary dwarfism
pituitary gland doesn’t produce enough HGH (affects all bones)
achondroplasia dwarfism
epiphyseal plates in long bones don’t respond well to HGH
bone remodeling
restructuring/restrengthening of bones occurs throughout life
2 types of bone remodeling
- bone deposition 2. bone resorption
bone deposition 1. is what 2. occurs when 3. what secretes what that stimulates production of what
- bone tissue added to bone making them denser and stronger 2. occurs when thyroid gland senses high blood calcium levels (caused by consuming calcium) 3. thyroid gland secretes calcitonin (hormone that stimulates production of osteoblasts) which returns blood calcium levels to normal
bone resorption 1. is what 2. occurs when 3. what secretes what that stimulates production of what
- bone tissue is broken down making the bone less dense and weaker 2. occurs when parathyroid glands sense low blood calcium levels (caused by not consuming calcium) 3. parathyroid glands secrete parathyroid hormone (stimulates production of osteoclasts) which returns blood calcium levels to normal
blood calcium level dictates what
whether bone deposition or bone reposition is occurring on our skeleton
Wolff’s law
- bone deposition is targeted to bones and regions of bones experiencing more weight and physical stress 2. bone reposition is targeted to bones and regions of bones where there’s a lack of weight and stress
4 stages of bone fracture repair
- blood clot forms in fracture site 2. connective tissue cells (fibroblasts, chondroblasts, osteoblasts) enter fracture site forming connective tissue callous 3. osteoblasts and osteoclasts replace connective tissue callous w/ spongy bone 4. osteoblasts and osteoclasts remodel spongy bone into compact bone tissue
rickets
occurs in children due to lack of calcium and/or vitamin D and causes deformed and brittle bones
osteomalacia
“adult rickets” occurs in adults due to lack of calcium and/or vitamin D and causes brittle and painful bones
osteoporosis 1. are what and lead to what 2. due to what 3. considered what
- porous/brittle bones leading to bone fractures 2. due to bone resorption out pacing bone deposition 3. considered to be a normal part of aging
11 risk factors for osteoporosis
- age 2. low calcium/vitamin D diet 3. certain meds 4. being female 5. asian or european ancestry 6. petite frame 7. sedentary lifestyle 8. family history 9. smoking 10. alcoholism 11. consuming phosphates