integumentary system Flashcards
3 main cell types in the epidermis
- keratinocytes
- basal cells
- melanocytes
keratinocytes
- are the most what
- filled with what
- bound together via what 2 means
- release what
most abundant cell type in the epidermis
filled w/ a cytoskeletal protein called keratin
cells are bound together via tight junctions and desmosomes
release vesicles filled w/ lipids via exocytosis
basal cells
- located where
- continuosly do what
- do what to the epidermis
- at the very bottom of the epidermis
- continuously divide to produce a new basal cell and a new keratinocyte cell
- regenerate the epidermis
melanocytes
- located where
- produce what
- release what
- what happens to what it releases
- in deep layers of epidermis
- produce the protein melanin
- release vesicles filled w/ melanin via exocytosis
- melanin is then taken up by keratinocytes
what’s a callous and how is it caused
a thickening of the epidermis caused by friction which stimulates basal cells to divide faster
what is eczema
any kind of skin inflammation
psoriasis
a condition where the immune system attacks and kills keratinocytes prematurely
dandruff
fungal infection of epidermis of scalp which kills keratinocytes prematurely
epidermis is what and made of what
superficial layer of skin made of about 50 layers of stratified aquamous epithelium
dermis is what and contains what 5 things
middle layer of skin containing
- blood vessels
- nerves
- sensory receptors
- hair follicles
- bodies of skin glands
2 regions of dermis
papillary region
reticular region
papillary region
- location
- made of
- function
- very large where
- upper region of dermis
- areolar connective tissue
- it binds the epidermis to the dermis via dermal papillae
- large in palms of hands and soles of feet giving rise to prints
reticular region
- location
- made of
- function
- what happens when its torn
- below papillary region
- dense irregular tissue
3, provides skin w/ toughness
- scar tissue forms stretch marks
hypodermis
- location
- made of
- function
- thickest where
- bottom layer of skin
- adipose connective tissue (where most of the body’s adipose tissue is located)
- cushions body, insulates heat and stores lipids
- butt and breast skin
3 pigmnets that determine skin color
melanin
hemoglobin
carotene
hemoglobin
red color protien in blood that gives skin its reddish color by flowing through see-through walls in capillaries in the dermis and hypodermis
carotene
type of vitamin A stored in skin
it is orange-yellowish giving skin that hue
comes from orange-yellowish vegetables
suntans are caused how
UV exposure stimulating melanocytes to produce and release more melanin
freckles
patches of skin where melanocytes produce more melanin
moles
like freckles but have more melanin causing them to have a raised surface
albinism
genetic condition where melanocytes can’t produce melanin
vitiligo
autoimmune condition where the immune system attacks and kills melanocytes
hair is made of what and list 6 of it’s functions
made of dead keratinocytes
- sense of touch
- sun protection
- protects eyes from debris
- keeps head warm
- eyebrows give rise to facial expressions
- prevents chaffing on scrotum
hair follicle
sheath that surrounds the hair root and holds it in the skin
hair matrix
- location
- made of what 2 things
- function
- bottom of hair follicle
- basal cells and melanocytes
- its where keratinocytes are made to grow hair
hair root plexus
nerve that wraps around the hair root and acticates touch sensation when the hair moves
dark or brown hair is caused by what
dark melanin and/or high amount of melanin
blond hair is caused by
bown melanin and pheomelanin (red color variety of melanin)
red hair is caused by
pheomelanin
grey hair is caused by
mix of white hair and colored hair
white hair is caused by
no melanin
what is the typical life span for a hair in the scalp
2 to 6 years
2 types of sweat glands
eccrine sweat glands
apocrine sweat glands
eccrine sweat glands
- location
- contain what 3 things
- stimulated by what 2 things
- almost all over body w/ high concentrations in forehead, palms and soles
- water, electrolytes, wastes (lactic acid, urea, carbon dioxide)
- stimulated by stress anh high body temperature
apocrine sweat glands
- located in what 4 areas
- contain what 5 things
- stimulated by what 2 things
- armpits, groin, face, nipples
- water, electrolytes, wastes, proteins, lipids
- stimulated by stress and sexual arrousal
body odor
- occurs where
- caused by what
- armpits and feet
- gasses produced by bacteria when they break down sweat molecules
sebaceous glands (oil glands)
- connected to what
- secrete what
- function
- hair follicles
- secrete sebum onto hair
- moisturizer to prevent skin and hair from cracking
pimple
infected sebaceous gland
tumor
abnormal mass/growth of cells
cancer cells
divide uncontrollably and interfere w/ their organ’s functioning and can potentially spread (metastasize)
metastasis
when cancer cells break off a tumor, travel through body fluid and form a new tumor somewhere else
3 types of skin cancer
- basal cell carcinoma
- squamous cell carcinoma
- melanoma
4 facts about basal cell carcinoma
- most common type of skin cancer
- tumors look like red moles
- doesn’t metastasize readily
- tumors of mutant basal cells
4 facts about squamous carcinoma
- look like warts
- form on head
- more serious that basal carcinoma
- tumors of keratinocytes
6 facts about melanoma
- most malignant
- look like weird moles
- metastasize readily
- difficult to treat
- tumors of mutant melanocytes
- have an ABCDE detection method
ABCDE detection method
A. tumors are assymetrical
B. tumors have an irregular border
C. tumors are multi-colored
D. tumors have a diameter bigger than a pencil
E. tumor elvolves in shape and size
5 skin cancer risk factors
- blue eyes
- light colored skin that doesn’t tan
- red or blond hair
- family history
5, multiple sunburns throughout life
5 causes of burns
- heat
- extreme cold
3 chemicals
- UV exposure
- electricity
1st degree burn
- damages what
- symptoms
- only damages epidermis
- redness, pain, heat
2nd degree burn
- damages what
- symptoms
- damage to epidermis and dermis
- redness, pain, heat, blistering
3rd degree burn
- damages what
- dangers of
- epidermis, dermis, hypodermis
- life-threatening because ther’s no barrier protecting body from microbial invasion