Skeletal System Flashcards
functions of skeletal system
support of body
protection of internal organs
levers for skeletal muscles to act
production of blood cells through bone marrow
storage of minerals
bone composition
composite material
- 70% calcium phosphate crystals (inorganic)
- 30% collagen fibres (organic)
remodels under influence of forces
calcium phosphate
strong but inflexible
ability to resist compressive stress
collagen
tough + flexible
ability to resist stretching, bending, + twisting stresses
anisotropic
bone (and wood) has different strength and hardness properties depending on its orientation
→ properties are different in different planes
mesenchymal cells
stem cells
undifferentiated
osteoprogenitor cells
stem cells - unspecialized mesenchymal cells
found in outer + inner layers of bone
differentiate into more specialized bone cells → osteoblasts
important role in fracture repair
osteoblasts
bone cells derived from osteoprogenitor cells
secrete osteoid
‘bone-producing cells’
osteocytes
osteoblasts that become trapped in hard bony tissue
mature bone cells
monitor + maintain protein levels + mineral contents of bony matrix
osteoclasts
large multinucleated bone cells
derived from precursor blood cells
secrete acids that erode bony matrix for release of amino acids + minerals in body fluids (blood)
osteiod
collageous material secreted from osteoblasts
unmineralized bone → will mineralize (calcify) to become bone
compact bone
relatively dense + solid
mainly found in diaphyses of long bones
spongy (trabecular) bone
open network of struts + plates
composed of trabeculae
interior bone tissue of short, flat, + irregular bones; epiphyses in long bones
endosteum
single layer of osteoblasts + fibrous tissue
inner layer (deeper tissue) lining medullary cavity
periosteum
single layer of osteoblasts + fibrous tissue
top outer layer (transparent)
medullary cavity
yellow marrow (adipocytes - fat)
+ red marrow (mature + immature red + white blood cells)
osteon
basic functional unit of mature compact bone
made up of Haversian systems: osteocytes organized in concentric layers around a central canal containing blood vessels
lamellae
parallel alignment of collagen into sheets to form calcified extracellular matrix
- concentric: concentric rings that form osteons
- circumferential: rings that line inner + outer surfaces of compact bone
- interstitial: areas of incomplete lamellae between osteons
lacunae
cavities between lamellae that contain osteocytes
trabeculae
irregular lattice arrangement of lamellae that surround red bone marrow
cartilage
type of connective tissue
dense network of collagen or elastic fibres
chondroblasts
deposit cartilage extracellular matrix
mature into chondrocytes
chondrocytes
sit in lacunae
found in cartilage
perichondrium
connective tissue covering surface of most cartilage