respiratory Flashcards

1
Q

functions

A

exchange of gas between atm and blood
- uptake of O2 + release of CO2
filtration, temperature regulation, + humidification of inspired air
olfaction = sense of smell
production of sound

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2
Q

respiratory area

A

~70 sq. m (750 sq. feet)

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3
Q

upper respiratory system

A

entry of air into body through mouth/nose to larynx
external nares → nasal vestibule → conchae → internal nares → nasopharynx → eustachian tube → oropharynx → laryngopharynx

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4
Q

external nares

A

nostrils
two holes leading into nasal cavity (one is larger)
nasal cavity = in visceral cranium
separated by septum (cartilage)

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5
Q

conchae

A

projections from lateral wall into nasal cavity
3 (top two = cartilage, lowest = bone)
turbinates when covered with mucous membrane

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6
Q

turbinates

A

turbulence of air
mucous membrane contains blood and moisture = warming + humidification of air
protects airway from cold air

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7
Q

internal nares

A

funnel air into pharynx
at the back of the nasal cavity
in line with end of hard palate (separation of oral + nasal cavities)

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8
Q

nasopharynx

A

nasal part of pharynx
contains eustachian tube

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9
Q

eustachian tube

A

connects nasopharynx to middle ear
air helps balance pressure of external forces squeezing eardrum (also movement from swallowing)

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10
Q

oropharynx

A

posterior to oral cavity

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11
Q

epiglottis

A

flap at posterior aspect of tongue
mobile structure = covers glottis leading to trachea when swallowing food

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12
Q

laryngopharynx

A

posterior to larynx
differentially direct air/food

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13
Q

protection of airway when swallowing

A

tongue pushes bolus into oropharynx
soft palate closes nasal cavity; laryngeal movement closes epiglottis to seal airway
pharygeal muscles push bolus into esophagus

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14
Q

lower respiratory system

A

below larynx
divided into conducting + respiratory portions
trachea branches into L + R primary bronchi
bronchi enter lungs at hilum → branch into secondary bronchi → tertiary bronchi → bronchioles → terminal bronchioles

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15
Q

hilum

A

root of lung
site where blood vessels, lymph vessels, nerves and airways enter and leave lungs
tail inferior to main entrance → often has vein (both lungs)

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16
Q

lungs

A

apex = top (above clavicle)
base = bottom (proximal to diaphragm)
oblique fissure separates inferior lobe from others

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17
Q

R lung

A

3 lobes = superior, middle, + inferior
horizontal fissure separates superior + middle lobes

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18
Q

L lung

A

2 lobes = superior + inferior
cardiac notch in medial surface = lung grows around heart
lingula: projection of superior lobe around heart (inferior to tissue of inferior lobe)

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19
Q

pleura

A

membrane surrounding lungs
outside layer = parietal pleura (inside of thoracic cage, on body wall)
inside layer = visceral pleura (covers outside of lungs)
forms pleural cavity in between two layers

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20
Q

pleural cavity

A

both layers of pleural membrane are serous = secrete fluid
fluid protects lungs from friction during expansion

21
Q

primary bronchi

A

direct air into lungs
divide into secondary

have thinner cartilage rings, more spaced out
R side = shorter (before branching), straighter, wider

22
Q

secondary bronchi

A

direct air into lobes
3 on R side; 2 on L side
divide into tertiary

23
Q

tertiary bronchi

A

direct air into segments of lungs within lobe

24
Q

bronchioles

A

airway projections
terminal bronchioles = smallest conducting passages

25
trachea
sits anterior to esophagus anterior surface covered by C-shaped cartilage rings (posterior surface = smooth muscle, between esophagus)
26
smooth muscle
in all conducting branches of airway but predominates in smaller airways (trachea → bronchioles) controls diameter of airway: allows broncho-constriction/dilation = movement of air constriction reduces airflow
27
conducting zone
trachea → terminal bronchioles no alveoli airways facilitate movement of air
28
respiratory zone
respiratory bronchioles → alveolar ducts (alveolar sacs) have alveoli airways conduct air and facilitate gas exchange
29
alveolar sacs
clustered alveoli fed by capillary network
30
airway walls
cartilage (in larger airways; helps keep airways open) smooth muscle elastic fibres
31
elastic fibres
lots, around all airways predominate in smaller airways and respiratory portion elastic recoil provides force for expiration
32
asthma attack
smooth muscle in wall of bronchioles contracts = narrowing of airways contraction caused by: parasympathetic stimulation + mediators of allergic reactions (histamine) muscle contraction reduces airflow bronchioles = most numerous airways → provide greatest resistance to airflow
33
emphysema
reduced ability to exhale air from lungs due to breakdown of alveolar walls = produces abnormally large air spaces lowered surface area for gas exchange → reduced respiratory efficiency reduced elastic recoil due to loss of elastic fibers causes: smoking, other irritants
34
respiratory epithelium
- pseudostratified epithelium line larger passages (nasal cavity, nasopharynx, large airways) - stratified squamous (non-keratinized) in oropharynx - gradually becomes simple in smaller tubes: simple columnar → cuboidal → squamous (in alveoli) stem cells located at base contains goblet cells = produce mucous apical surface has lots of cilia mucous layer floats on serous layer
35
alveolar wall
between alveolar air space and RBCs alveolar epithelium (type I cells) → fused basement membrane → capillary endothelium → capillary lumen
36
how many plasma membranes does an oxygen molecule cross to pass from air space to bind a hemoglobin molecule in a RBC
5 across alveolar cell: - luminal membrane - basolateral membrane across endothelial cell: - basolateral membrane (facing basal lamina) - luminal membrane (facing inside capillary) into RBC - rbc membrane
37
type I alveolar cells
simple squamous epithelium line alveoli
38
type II alveolar cells
secrete surfactant embedded in alveolar epithelium
39
surfactant
lowers surface tension of alveolar fluid prevents alveolar walls from sticking together + collapsing (facilitates opening of alveoli)
40
respiratory distress syndrome
occurs in children born prematurely under-developed type II alveolar cells lack surfactant = alveoli cannot inflate properly leads to insufficient oxygenation of blood
41
alveolar macrophages
"roomba" ingest debris in alveoli to prevent interference with surface gas exchange are expelled into airways → become trapped in mucous sheets → carried toward pharynx by ciliary action → expectorated or swallowed
42
pulmonary arteries
travel with airways → branch to reach alveoli carry deoxygenated blood
43
pulmonary veins
travel in interlobular connective tissue take direct path to return to L atrium carry oxygenated blood
44
lymphatics
travel in interlobular connective tissue
45
alveolar capillaries
form network surrounding alveoli
46
muscles of quiet inhalation
diaphragm: contracts to flatten = ↑ vertical diameter of thoracic cavity external intercostals: lift ribs superiorly + move sternum anteriorly
47
muscles of quiet exhalation
no muscles relaxation of muscles contracted during insp elastic recoil of lung tissue + thoracic wall
48
muscles of forced inhalation
accessory muscles sternocleidomastoid = elevates sternum scalenes = elevate ribs 1 + 2 pectoralis minor = elevates ribs 3-5
49
muscles of forced exhalation
internal intercostals (in between ribs) abdominal muscles = move inferior ribs down + compress viscera to push diaphragm superiorly