Side Effects/interactions

Question 1

Two antibiotics that cause long QT

Answer 1

Macrolide and fluroquinolones

Question 2

SSRIs in regard to pregnancy

Answer 2

Paroxetine has CV malformation risk

Fluoxetine has small increased risk of congenital malformations, SA, reduced birth wt and gestational period

Question 3

SSRI with highest risk of QT prolongation

Answer 3

Citalopram

(Sertraline lowest)

Question 4

Med precipitating gout

Answer 4

Diuretic
Aspirin

Question 5

OCP interacts with

Answer 5

Anticonvulsants, antiretrovirals, rifsmpin

Question 6

Clozapine

Answer 6

Agranulocytosis, seizures, myocarditis, cardiomyopathy

Follow up laps every three months

Question 7

SE of anti-epileptics

Answer 7

Drowsiness
insomnia
Dizziness
Vertigo
Cognitive impairment
Agitation
GI symptoms
HypoNa
Parasthesia

Rash after lamotrigene to valproic acid
Reduced effectiveness in OCP and warfarin

Question 8

Meds causing infertility in males

Answer 8

Marijuana
Ketoconazole
Spironolactone
ETOH

Question 9

PDE5i

Answer 9

Flushing
Headache
Dyspepsia
Nasal congestion

Rare: MI, priapism, QT prolongation

Question 10

Oestrogen side effects

Answer 10

Gynaecomastia
Irregular bleeding (increased bleed)
Endometrial, breast carcinoma
Headaches (migraine)
Nausea, vomiting
Bloating and oedema
High blood pressure
Breast tenderness
DVT

Question 11

Progestin side effects

Answer 11

Acne
Weight gain
Fatigue
Depression
Low libido

Question 12

Levodopa/carbidopa

Answer 12

Impulse control issues
Psychotic symptoms
Dyskinesia
NV
GI upset
Orthostatic hypotension
Somnolence

Question 13

Using betalactams in mono

Answer 13

Morbiform rash

Question 14

Warfarin

Answer 14

Interactions: NSAID, acetaminophen, alcohol, amiodarone, allopurinol, fibrate, antibiotics

Decreased effectiveness: phenytoin, vitamin K, MMI/PTU, rifampin