Short Term Control of Blood Pressure Flashcards

1
Q

What is the most essential equation in cardio?

A

MAP= CO x TPR

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2
Q

What is the driving force pushing blood through the circulation?

A

MAP

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3
Q

Why does MAP have to regulated?

A
  • Too low= syncope

- Too high= hypertension

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4
Q

Where are the baroreceptors located?

A
  • Aortic arch

- Internal carotid arteries

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5
Q

What are baroreceptors?

A

Stretch receptors which detect changes in pressure

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6
Q

How does MAP affect baroreceptors?

A
  • Low MAP will cause a short burst of action potentials
  • Elevated MAP will cause APs to be fired in quick succession as the vessels will be constantly stretched and therefore the receptors will constantly be sending signals
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7
Q

What nerve do impulses from the baroreceptor on the aortic arch go via?

A

Vagus nerve

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8
Q

What nerve do impulses from the carotid sinus baroreceptors go via?

A

Glossopharyngeal nerve

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9
Q

What area of the brain are impulses from the glossopharyngeal and vagus nerves received?

A

Medullary cardiovascular centres

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10
Q

What effect do sympathetic nerves have on the sinoatrial node?

A

Increases heart rate

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11
Q

What effect do parasympathetic nerves have on the sinoatrial nerve?

A

Decrease heart rate

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12
Q

What effect do sympathetic nerves have on blood vessels?

A

Vasocnstriction and arteriolar constriction

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13
Q

What happens if veins are constricted?

A

Increase preload

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14
Q

What happens if arterioles are constricted?

A

Increase TPR

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15
Q

What effect do sympathetic nerves have in the ventricles?

A
  • Increases strength of contraction
  • Increases conduction velocity
  • Increase stroke volume
  • Increase cardiac output
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16
Q

What other inputs to the medullary cardiovascular centres are there?

A
  • Cardiopulmonary baroreceptors
  • Central chemoreceptors
  • Chemoreceptors in muscle
  • Joint receptors
  • Higher centres
17
Q

Why do central chemoreceptors affect the CV system?

A

If there is more oxygen in the blood the body will respond in order to get it through systemic circulation quicker

18
Q

What do muscular chemoreceptors respond to?

A

Physical activity

19
Q

What do joint receptors respond to?

A

Physical activity

20
Q

How will exercise affect MAP?

A

Increase

21
Q

What are central chemoreceptors, chemoreceptors in muscle and joint receptors forms of?

A

Negative feedback control

22
Q

How are higher centres involved in the CV system?

A

They anticipate change and respond with feed forward controls

23
Q

What does regulation of blood pressure in the long term revolve around?

A

Blood volume

24
Q

What are the main sensors in the regulation of blood pressure in the long term?

A

Cardio-pulmonary baroreceptors

25
Q

What are most of the effects of the cardio-pulmonary baroreceptors controlled by?

A

Hormones

26
Q

What do the hormones stimulated by the cardio-pulmonary baroreceptors act on?

A

Blood vessels and the kidneys

27
Q

What are the effects of standing up?

A

Increased hydrostatic pressure causes pooling of blood in veins/venules of feet and legs

28
Q

What do the effects of standing up cause?

A
  • Decreased VR
  • Decreased EDV
  • Decreased preload
  • Decreased SV
  • Decreased CO
  • Decreased MAP
  • Decreased baroreceptor firing rate
29
Q

What 2 effects does the reflect response exhibit?

A
  • Decreased vagal tone

- Increased sympathetic tone

30
Q

What are the effects of decreased vagal tone?

A
  • Increased heart rate

- Increased CO

31
Q

What are the effects of increased sympathetic tone?

A
  • Increased heart rate and CO
  • Increased contractility, SV and CO
  • Increased venoconstriction, VR, EDV, SV and CO
  • Increased arteriolar constriction and TPR
32
Q

What is the Valsalva manoeuvre?

A

Forced expiration against a closed glottis

33
Q

What is the purpose of the Valsalva manoeuvre?

A

To increase pressure in the thorax and abdomen

34
Q

What a change in thoracic pressure transmitted through in the Valsalva manoeuvre?

A

Aorta

35
Q

What does an increase in thoracic pressure?

A

Decreased

  • VR
  • EDV
  • SV
  • CO
  • MAP
36
Q

What detects a decrease in MAP?

A

Baroreceptors

37
Q

What reflex do the baroreceptors initiate?

A

Increased CO and TPR

38
Q

How is normal restored in the Valsalva manoeuvre?

A

VR is restored so SV increases