Sexually Transmitted Infections Flashcards

1
Q

describe Gonorrhoeae’s discharge

A

usually males

thick purulent

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2
Q

Pelvic Involvment from STIs cause?

A

Pelvic Inflammatory Disease

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3
Q

Gonorrhoea what kind of bacteria?

A

gram -ve diplococci

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4
Q

Gonorrhoea adhere to?

A

columnar epithelial cells

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5
Q

why younger women more likely to get Gonorrhoea?

A

their ectocervix has more columnar epithelial cells

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6
Q

Gonorrhoea asymptomatic how many % females vs. males?

A

females: 80%
males: 10%

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7
Q

Gonorrhoea antibiotic resistance how?

A

plasmid exchange with throat commensals during oral sex

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8
Q

get peri-hepatitis (fitz-hugh-curtis syndrome) with what infection?

A

disseminated Gonorrhoea (violin string adhesions)

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9
Q

2 big disseminated symptoms of Gonorrhoea?

A

maculopapular rash

peri-hepatitis

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10
Q

what happens in pelvic inflammatory disease?

A

get fever
tubal scarring
infertility

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11
Q

neonatal Gonorrhoea opthalmia happens when? describe presentation. if untreated?

A

day 2-5
gross purulent conjunctivitis
could cause perforation and blindness if untreated

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12
Q

neonatal Gonorrhoea opthalmia treatment?

A

systemic cefotaxime, not topical

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13
Q

what is thayer-martin agar for?

A

inhibits microbiota

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14
Q

Gonorrhoea urine collection how?

A

first void urine

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15
Q

Gonorrhoea 50% co-infection with?

A

chlamydia

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16
Q

prevention of Gonorrhoea?

A

barrier contraception

contact tracing

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17
Q

what is the infectious part of chlamydia trachomatis called?

A

elementary bodies

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18
Q

chlamydia trachomatis adheres to?

A

columnar epithelials

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19
Q

chlamydia trachomatis what kind of bug?

A

obligate intracellular parasite

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20
Q

chlamydia trachomatis serovars: what are A-C? D-K? L 1-3?

A

A-C: ocular (Trachoma)
D-K: genital infection
L 1-3: lymphogranuloma venereum

21
Q

two forms of chlamydia trachomatis in life cycle?

A

elementary bodies: infectious, non replicating, hardy

reticulate bodies: metabolically active, replicate

22
Q

what is most common STI?

A

chlamydia trachomatis

23
Q

chlamydia trachomatis asymptomatic or symptomatic? cause what in females/males?

A

usu asymptomatic

males: urethritis
females: cervicitis

24
Q

chlamydia trachomatis symptoms in males?

A

clear discharge
dysuria
testicular pain
prostatitis

25
Q

lymphogranuloma venereum caused by?

A

chlamydia trachomatis

26
Q

lymphogranuloma venereum presentation?

A

ulcerative genital lesion get suppurative inguinal lymphadenopathy with systemic sx

27
Q

neonatal chlamydia trachomatis 2 main presentation:

A

conjunctivitis: 2-28 days, can be hemorrhagic
Pneumonia: 2-8 weeks: stacatto cough

28
Q

chlamydia trachomatis treatment?

A

1g Azithromycin or 100mg doxycycline bid 2/52

29
Q

chlamydia trachomatis at end of treatment need?

A

test of cure

30
Q

Trichomonas vaginalis what kind of bug?

A

flagellated protozoon

31
Q

Trichomonas vaginalis presentation?

A

asymptomatic usually

frothy green-yellow itchy vaginal discharge

32
Q

Trichomonas vaginalis does what to pH of vagina?

A

increases >5.0

33
Q

Trichomonas vaginalis causes genital inflam which can predispose you to what?

A

HIV acquisition

34
Q

Trichomonas vaginalis marker for?

A

high-risk sexual activity

35
Q

when do you get strawberry cervix?

A

Trichomonas vaginalis

36
Q

Trichomonas vaginalis testing? 3 things:

A

high vaginal swab
urine-PCR
pap smear

37
Q

Trichomonas vaginalis treatment?

A

metronidazole

tinidazole

38
Q

what is Treponema pallidum?

A

Syphilis

39
Q

primary Treponema pallidum (syphilis) presentation?

A

1-2 cm painless chancre then heals

40
Q

what is secondary Treponema pallidum (syphilis) presentation?

A

disseminated rash on palms, heels, face, scalp

41
Q

describe the 2 latent stages of Treponema pallidum (syphilis)?

A

early latent: symptomatic, +++ infectious secretions

late latent: after 2 years, less infectious, harder to treat

42
Q

what is tertiary Treponema pallidum (syphilis)?

A

10-30 years later you can get infection in aorta (dissections), joints, neurosyphilis

43
Q

Treponema pallidum (syphilis) AKA?

A

The great mimicker.

44
Q

Treponema pallidum (syphilis) dx via?

A

serology

45
Q

Mycoplasma Genitalium genome? cell wall? characteristics?

A

smallest genome
no cell wall
hard to culture
antibiotic resistant

46
Q

Treponema pallidum (syphilis) what shape of bacteria?

A

spirochete

47
Q

Mycoplasma Genitalium interaction in body?

A

attaches and taken into cell and protected from immune response

48
Q

Mycoplasma Genitalium causes what in women? 4 things

A

cervicitis
acute endometritis
PID
predispose to HIV

49
Q

Mycoplasma Genitalium treatment?

A

Azithromycin