Sexually Transmitted Infections Flashcards
describe Gonorrhoeae’s discharge
usually males
thick purulent
Pelvic Involvment from STIs cause?
Pelvic Inflammatory Disease
Gonorrhoea what kind of bacteria?
gram -ve diplococci
Gonorrhoea adhere to?
columnar epithelial cells
why younger women more likely to get Gonorrhoea?
their ectocervix has more columnar epithelial cells
Gonorrhoea asymptomatic how many % females vs. males?
females: 80%
males: 10%
Gonorrhoea antibiotic resistance how?
plasmid exchange with throat commensals during oral sex
get peri-hepatitis (fitz-hugh-curtis syndrome) with what infection?
disseminated Gonorrhoea (violin string adhesions)
2 big disseminated symptoms of Gonorrhoea?
maculopapular rash
peri-hepatitis
what happens in pelvic inflammatory disease?
get fever
tubal scarring
infertility
neonatal Gonorrhoea opthalmia happens when? describe presentation. if untreated?
day 2-5
gross purulent conjunctivitis
could cause perforation and blindness if untreated
neonatal Gonorrhoea opthalmia treatment?
systemic cefotaxime, not topical
what is thayer-martin agar for?
inhibits microbiota
Gonorrhoea urine collection how?
first void urine
Gonorrhoea 50% co-infection with?
chlamydia
prevention of Gonorrhoea?
barrier contraception
contact tracing
what is the infectious part of chlamydia trachomatis called?
elementary bodies
chlamydia trachomatis adheres to?
columnar epithelials
chlamydia trachomatis what kind of bug?
obligate intracellular parasite
chlamydia trachomatis serovars: what are A-C? D-K? L 1-3?
A-C: ocular (Trachoma)
D-K: genital infection
L 1-3: lymphogranuloma venereum
two forms of chlamydia trachomatis in life cycle?
elementary bodies: infectious, non replicating, hardy
reticulate bodies: metabolically active, replicate
what is most common STI?
chlamydia trachomatis
chlamydia trachomatis asymptomatic or symptomatic? cause what in females/males?
usu asymptomatic
males: urethritis
females: cervicitis
chlamydia trachomatis symptoms in males?
clear discharge
dysuria
testicular pain
prostatitis
lymphogranuloma venereum caused by?
chlamydia trachomatis
lymphogranuloma venereum presentation?
ulcerative genital lesion get suppurative inguinal lymphadenopathy with systemic sx
neonatal chlamydia trachomatis 2 main presentation:
conjunctivitis: 2-28 days, can be hemorrhagic
Pneumonia: 2-8 weeks: stacatto cough
chlamydia trachomatis treatment?
1g Azithromycin or 100mg doxycycline bid 2/52
chlamydia trachomatis at end of treatment need?
test of cure
Trichomonas vaginalis what kind of bug?
flagellated protozoon
Trichomonas vaginalis presentation?
asymptomatic usually
frothy green-yellow itchy vaginal discharge
Trichomonas vaginalis does what to pH of vagina?
increases >5.0
Trichomonas vaginalis causes genital inflam which can predispose you to what?
HIV acquisition
Trichomonas vaginalis marker for?
high-risk sexual activity
when do you get strawberry cervix?
Trichomonas vaginalis
Trichomonas vaginalis testing? 3 things:
high vaginal swab
urine-PCR
pap smear
Trichomonas vaginalis treatment?
metronidazole
tinidazole
what is Treponema pallidum?
Syphilis
primary Treponema pallidum (syphilis) presentation?
1-2 cm painless chancre then heals
what is secondary Treponema pallidum (syphilis) presentation?
disseminated rash on palms, heels, face, scalp
describe the 2 latent stages of Treponema pallidum (syphilis)?
early latent: symptomatic, +++ infectious secretions
late latent: after 2 years, less infectious, harder to treat
what is tertiary Treponema pallidum (syphilis)?
10-30 years later you can get infection in aorta (dissections), joints, neurosyphilis
Treponema pallidum (syphilis) AKA?
The great mimicker.
Treponema pallidum (syphilis) dx via?
serology
Mycoplasma Genitalium genome? cell wall? characteristics?
smallest genome
no cell wall
hard to culture
antibiotic resistant
Treponema pallidum (syphilis) what shape of bacteria?
spirochete
Mycoplasma Genitalium interaction in body?
attaches and taken into cell and protected from immune response
Mycoplasma Genitalium causes what in women? 4 things
cervicitis
acute endometritis
PID
predispose to HIV
Mycoplasma Genitalium treatment?
Azithromycin