Histology - Female Flashcards
ovary attached to?
posterior face of broad ligament
Ovary is anchored by 2 ligaments?
Ovarian to uterus
Suspensory to pelvic wall
oocytes are where in the ovary?
outer cortex of ovary
what is the cortical stroma of the ovary made of?
CT
scattered smooth muscles
ovarian surface has what kind of cells?
simple epithelium squamous or cuboidal
what is deep to the ovarian surface epithelium?
tunica albuginea
70% of ovarian tumours come from which layer?
ovarian surface epithelium
how many oocytes at birth?
0.5 million
how many oocytes in embryo ovary??
5 million
oocyte arrested in?
prophase of meiosis 1
primordial oocytes surrounded by?
follicle cells surrounded by basal lamina (type IV collagen)
primary oocyte is surrounded by what within follicle cell layer?
zona pellucida
enlarging primary oocyte: what happens to follicular cells?
become cuboidal, multilayered granulosa cells
what surrounded the granulosa cells in primary oocytes?
stromal cells that become theca interna and externa
what happens in secondary follicle? appearance?
Antrum forms
suspended on stalk of grnulosa cells
after release of oocyte, what do the granulosa cells form around it?
corona radiata
mature follicle callled?
Graafian follicle (1cm)
What happens to oocyte under LH surge?
complete meiosis 1, becomes secondary oocyte
how is corpus luteum formed?
stromal, granulosa and thecal cells invade cavity,
why is corpus luteum yellow?
lipid as precursor to sex steroids
expanded opening of fallopian tube?
infundibulum
describe the Ampulla of fallopian tube
ciliated and mesothelium
describe the isthmus of fallopian tube
thicker smooth muscle, smaller lumen, better for peristaltic wave propagation
uterine tube secretory?
yes secreted nutrients for oocyte
fertilisation occurs where? usually remains where for 3 days?
ampulla fertilisation
isthmus for 3 days
3 layers of uterus?
- endometrium (mucosa)
- myometrium
- perimetrium
perimetrium made of?
mesothelium
elastic CT
which of the 3 uterine layer respond to cyclic hormonal changes?
myometrium
endometrium
3 layers of myometrium: and their direction
- inner longitudinal
- outer longitudial
- middle circular and vascular
how is myometrium post pregnancy?
thickened wall post first preg
how does uterus accommodate in preg? 3 ways
- enlarging individual smooth muscle cells
- more smooth muscle cells
- increasing CT
Endometrium is mixtures of?
ciliated
secretory columnar simple epithelium
endometrium what layers?
functional (sloughed off)
basal (regenerates)
endometrium growth driven by?
estrogen
endometrium secretions contain?
mucoid glycogen
endocervix cell type?
simple columnar, glandular
ectocervix cell type?
stratified squamous, non glandular
vaginal secretions during ovulation come from?
endocervix: serous and copious
where is the risk of cervical cancer location?
transition between simple and stratified squamous epitheliums
glands in vagina?
Nope. all in cervix and vestibule
vagina what kind of cells?
non keratinized stratified squamous, mucossa with partly erectile lamina propria
most superficial cells in ectocervix and vagina when shed retain?
their nuclei
what s embedded in dense breast tissue?
adipose tissue
multiple mammary glands
at puberty what happens to glands?
extend and breast enlarges
how many mammary glands per breast?
15-20
what is TDLUs?
terminal duct lobular units, where the ducts end up together
intralobular breast stroma contains?
no adipose
responsive to hormones
describe mammary glands in follicular and luteal phase
follicular: less dense. cuboidal
luteal: more columnar: some secretions
what surrounds the columnar glandular epithelial cels in breast?
myoepithelial cells
in preg, what happens to mammary glands?
large cuboidal epithelial
enlarged breast
terminal ductules elongate and branch
Human milk is full of?
protein, IgA
human milk is low on?
lipid and carbohydrate
suckling does what reflex?
inhibits PIH in hypothalamus
increases oxytocin
squeeze TDLUs
mammary gland sinuses do what?
stores milk
what happens to breasts in menopause?
involute as secretory cells disappear