Histology - Female Flashcards

1
Q

ovary attached to?

A

posterior face of broad ligament

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2
Q

Ovary is anchored by 2 ligaments?

A

Ovarian to uterus

Suspensory to pelvic wall

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3
Q

oocytes are where in the ovary?

A

outer cortex of ovary

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4
Q

what is the cortical stroma of the ovary made of?

A

CT

scattered smooth muscles

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5
Q

ovarian surface has what kind of cells?

A

simple epithelium squamous or cuboidal

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6
Q

what is deep to the ovarian surface epithelium?

A

tunica albuginea

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7
Q

70% of ovarian tumours come from which layer?

A

ovarian surface epithelium

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8
Q

how many oocytes at birth?

A

0.5 million

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9
Q

how many oocytes in embryo ovary??

A

5 million

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10
Q

oocyte arrested in?

A

prophase of meiosis 1

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11
Q

primordial oocytes surrounded by?

A

follicle cells surrounded by basal lamina (type IV collagen)

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12
Q

primary oocyte is surrounded by what within follicle cell layer?

A

zona pellucida

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13
Q

enlarging primary oocyte: what happens to follicular cells?

A

become cuboidal, multilayered granulosa cells

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14
Q

what surrounded the granulosa cells in primary oocytes?

A

stromal cells that become theca interna and externa

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15
Q

what happens in secondary follicle? appearance?

A

Antrum forms

suspended on stalk of grnulosa cells

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16
Q

after release of oocyte, what do the granulosa cells form around it?

A

corona radiata

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17
Q

mature follicle callled?

A

Graafian follicle (1cm)

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18
Q

What happens to oocyte under LH surge?

A

complete meiosis 1, becomes secondary oocyte

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19
Q

how is corpus luteum formed?

A

stromal, granulosa and thecal cells invade cavity,

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20
Q

why is corpus luteum yellow?

A

lipid as precursor to sex steroids

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21
Q

expanded opening of fallopian tube?

A

infundibulum

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22
Q

describe the Ampulla of fallopian tube

A

ciliated and mesothelium

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23
Q

describe the isthmus of fallopian tube

A

thicker smooth muscle, smaller lumen, better for peristaltic wave propagation

24
Q

uterine tube secretory?

A

yes secreted nutrients for oocyte

25
fertilisation occurs where? usually remains where for 3 days?
ampulla fertilisation | isthmus for 3 days
26
3 layers of uterus?
1. endometrium (mucosa) 2. myometrium 3. perimetrium
27
perimetrium made of?
mesothelium | elastic CT
28
which of the 3 uterine layer respond to cyclic hormonal changes?
myometrium | endometrium
29
3 layers of myometrium: and their direction
1. inner longitudinal 2. outer longitudial 3. middle circular and vascular
30
how is myometrium post pregnancy?
thickened wall post first preg
31
how does uterus accommodate in preg? 3 ways
1. enlarging individual smooth muscle cells 2. more smooth muscle cells 3. increasing CT
32
Endometrium is mixtures of?
ciliated | secretory columnar simple epithelium
33
endometrium what layers?
functional (sloughed off) | basal (regenerates)
34
endometrium growth driven by?
estrogen
35
endometrium secretions contain?
mucoid glycogen
36
endocervix cell type?
simple columnar, glandular
37
ectocervix cell type?
stratified squamous, non glandular
38
vaginal secretions during ovulation come from?
endocervix: serous and copious
39
where is the risk of cervical cancer location?
transition between simple and stratified squamous epitheliums
40
glands in vagina?
Nope. all in cervix and vestibule
41
vagina what kind of cells?
non keratinized stratified squamous, mucossa with partly erectile lamina propria
42
most superficial cells in ectocervix and vagina when shed retain?
their nuclei
43
what s embedded in dense breast tissue?
adipose tissue | multiple mammary glands
44
at puberty what happens to glands?
extend and breast enlarges
45
how many mammary glands per breast?
15-20
46
what is TDLUs?
terminal duct lobular units, where the ducts end up together
47
intralobular breast stroma contains?
no adipose | responsive to hormones
48
describe mammary glands in follicular and luteal phase
follicular: less dense. cuboidal luteal: more columnar: some secretions
49
what surrounds the columnar glandular epithelial cels in breast?
myoepithelial cells
50
in preg, what happens to mammary glands?
large cuboidal epithelial enlarged breast terminal ductules elongate and branch
51
Human milk is full of?
protein, IgA
52
human milk is low on?
lipid and carbohydrate
53
suckling does what reflex?
inhibits PIH in hypothalamus increases oxytocin squeeze TDLUs
54
mammary gland sinuses do what?
stores milk
55
what happens to breasts in menopause?
involute as secretory cells disappear