Serous fluid Flashcards
Accumulation of fluid between membranes
Effusion
Disruption of fluid production and regulation (not inflammatory)
Transudate
Hypoproteinemia, CHF, Nephrotic syndrome effusion
Transudate
Direct damage to the membrane (inflammation caused)
Exudate
Transudate vs. Exudate: Fluid:serum protein ratio (most reliable) <0.5
Transudate
Transudate vs. Exudate: Fluid:serum LD ratio (most reliable) <0.6
Transudate
Pleural fluid cholesterol of exudate
> 45-60
Serum ascites albumin gradient (SAAG) of transudate
≥1.1
Rivalta’s test (+)
Exudate
Recommended to detect transudate of hepatic origin
SAAG
Method of collection for pleural fluid
Thoracentesis
Method of collection for pericardial fluid
Pericardiocentesis
Method of collection for ascitic fluid (peritoneal)
Paracentesis
Turbid white pleural fluid
Microbial infection (TB)
Brown color of pleural fluid
Rupture of amoebic liver abscess
Black color of pleural fluid
Aspergillosis
Milky color of pleural fluid
Chylous material, pseudochylous material
Bloody color of pleural fluid
Hemothorax, hemorrhagic effusion
Appearance of pseudochylous
Milky, green tinge/gold paint
Increased lymphocytes in pleural fluid indicates
Chylous effusion
Hemothorax distribution of blood
Uneven
Hemothorax Hct value
Pleural fluid ≥1/2 of whole blood
Hemorrhagic effusion hematocrit value
Pleural fluid < Whole blood
Significance of neutrophil in pleural fluid
Pneumonia, pancreatitis, pulmonary infarction
Significance of eosinophil in pleural fluid
Pneumothorax, hemothorax, allergic reaction, parasitic infections
Significance of mesothelial cells in pleural fluid
Normal, reactive forms no sig, decreased in TB
Adenosine deaminase in pleural fluid indicates
Malignancy, tuberculosis
Amylase in pleural fluid indicates
Pancreatitis, esophageal rupture, malignancy
Tumor marker for colon cancer
CEA
Tumor marker for ovarian, metastatic uterine cancer
CA 125
Tumor marker for breast cancer
CA 15-3, CA 549
Tumor marker for lung cancer, breast cancer, urinary bladder cancer
CYFRA 21-1
Green color of peritoneal ascitic fluid
Bile, pancreatic, gall bladder disorders
Milky ascitic fluid
Lymphatic trauma and blockage
Peritoneal lavage RBC count indicating blunt trauma
> 100,000 RBCs/μL
Glucose in peritoneal fluid
Tubercular peritonitis, malignancy
Contains concentric striations of collagen-like material seen in benign conditions and associated with ovarian and thyroid carcinomas
Psammoma bodies