Seronegative Inflammatory Arthopathies Flashcards
What is ankylosing spondylitits?
Chronic Inflammatory condition affecting mainly spine and sacroiliac joints
What condition can present with a question mark spine? (loss of lumbar lordosis and increase in thoraric kyphosis)
Ankylosing spondylitis
Who is most likely to present with AS and what is the most classical presentation?
Young male - late teens to early 20s
3mnth onset of lower back/buttock pain and stiffness
AM stiffness lasting at least 30mins
Why does AS sometimes present with chest pain?
Fusion of the costovertebral joints
What gene is present in 90% of AS patients?
HLA B27
What test can be done on AS patients to test for lumbar restriction?
Schober’s test
What condition is associated with bamboo spine on XR?
What causes this to happen?
AS
Syndesmophytes - areas of bone growth where ligament normally inserts
What drug management can be used for AS?
- NSAIDs !!
Steroids during flareups
Anti-TNF
Name 4 extra manifestations of AS?
- Anterior uveitis
- Chest pain
- Enthesitis (leads to plantar fascitis + achielles tendonitis)
- aortitis
Define enthesitis
Define dactylitis
What condition can these be seen in?
Enthesitis - inflammation of the entheses (point where tendon/ligament insert into bone)
Dactylitis - severe inflammation of finger and toe joints
Seronegative inflam conditions
In what condition may the patient suffer from a triad of symptoms known as Reiter’s syndrome?
What are the symptoms?
What joint is most commonly affected?
Reactive arthritis (usually secondary to GU infection)
- Urethritis
- Uveitis
- Arthritis
Knee
What kind of arthritis can follow alongside IBD?
Enteropathic arthritis
What types of arthritis occur as large asymmetrical oligoarthritis?
Enteropathic
Reactive
Psoriatic arthritis
What other symptoms are found alongside arthritis in psoriatic arthritis?
Nail changes
- pitting
- onycholysis (lifting off nail bed)
- enthesitis
- dactylitis
How is psoriatic arthritis managed?
Similarly to RA - with DMARDs
