Sepsis

Question 1

What is the definition of systemic inflammatory response syndrome?

Answer 1

• 2 or more of the following
• Temp over 38 or under 36,
• Heart rate over 90
• Respiratory rate over 20
• WCC over 12,000 or under 4000

Question 2

What is the definition of the following:
- Sepsis
- Severe sepsis,
- Septic shock

Answer 2

• Sepsis: SIRS and presumed infection.
• Severe sepsis: Sepsis plus evidence of organ dysfunction. (definition to give in exams)
• Septic shock: Severe sepsis with hypotension or lactic acidosis.

Question 3

What is the clinical presentation of sepsis?

Answer 3

• Fever, breathlessness, headache, nausea and vomiting, diarrhoea.
• Tachycardia, hypotension, pyrexia, peripheral vasodilation, hypoxia, tachypnoea.

Question 4

What is the sepsis 6?

Answer 4

BUFALO
- Take bloods and culture,
- Measure lactate
- Administer oxygen,
- Administer IV antibiotics
- Administer IV fluids,
- Monitor urine output

Question 5

What is the treatment for meningitis?

Answer 5

• Ceftriaxone as it has good CNS penetration and active against gram negatives

Question 6

What is the qSOFA score?

Answer 6

Patient gets 1 point for each of the following:
- Altered mental status
- resp rate over 22
- Systolic blood pressure under 100mmhg