Semiquantitative analysis of urine Flashcards
What is the method of semiquantitative diagnostics based on?
mostly on indicator strips and their evaluation by the naked eye
What is the test based on?
Colour alterations using indicators of corresponding substance
Whan can the diagnostic kits PHAN be used for?
To detect several parameters at once, including glucose and proteins.
Why should there not be any glucose under physiological conditions?
Transport systems in the PROXIMAL tubulus allow for its complete reabsorbtion.
What small substances can pass the glomerula filter and appear in the urine?
small proteins and peptides –>can include digestive enzymes like pepsin, chymosin, trypsin, amylase
Which digestive enzymes’ concentration in urine can have a great clinical significance?
digestive enzymes like pepsin, chymosin, trypsin, amylase
Tubular transport maximum (Tm) ?
threshold level of transport systems –> for substances which are transported actively by transporters (glucose)
What happens to a substance that is filtrated beyond its Tm?
Will not be reabsorbed and escapes into urine
What regulates glucose reabsorbtion?
Plasma level is governed by endocrine regulation, not the kidney.
How much of glucose is reabsorbed?
All glucose will be reabsorbed up to Transport maximum, independently of the plasma level.
How does kidneys regulate glucose level?
They do not regulate it, only maintain the level set by other mechanisms.
Which compartments must glucose pass to enter the peritubular capillaries?
- luminal cell membrane
- cytosol
- basolateral cell membrane
- interstitial fluit
- capillary wall
What may cause false negative regarding glucose in urine?
A high consentration of ascorbic acid.
