Seizures Flashcards
1
Q
Brain tumors cause seizures in this age group
A
elderly
2
Q
When do you get an EEG for seizing patients?
A
always
3
Q
Why do you do a urine pregnancy screen for seizing patients?
A
affects Tx
4
Q
Carbamazepine
- MOA
- indications
A
- stabilitzes inactivated VG Na+ channels
- focal/partial and secondarily generalized seizures (not for absence and myclonic)
5
Q
Ethosuximide
- MOA
- indications
A
- antagonist for VG T-type dependent Ca2+ channel, works on thalamic neurons
- absence (generalized, nonconvulsive)
6
Q
Levetriacetam
- MOA
- indications
A
- SV2A interaction, inhibits Glu, promotes GABA
- focal, primary or secondary generalized tonic-clonic, myoclonic
7
Q
Phenytoin
- MOA
- indications
A
- stablizes inactivated VG Na+ channels
- partial and secondary generalized tonic-clonic
- bad drug about drug interactions*
8
Q
Topiramate
- MOA
- indications
A
- AMPA-kainate subtypes of GluR + increased VG Na+ channel inactivation
- focal and primarily generalized tonic-clinic seizures
9
Q
Valproic acid
- MOA
- indications
A
- multiple, NMDA antagonist
- most