Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Neuro Block 5-RG > CNS Tumors > Flashcards

CNS Tumors Flashcards

1
Q

What percentage of CNS tumors are mets?

A

70%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the most common CNS tumor in adults?

A

gliobalstoma multiforme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Metastasized lesions are usually found singly/present in groups

A

groups

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pleomorphic

A

variable shaped cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Adjuvant therapy

A

following primary treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Adult vs. child tumor locations

A

adult: supratentorial 70%
children: posterior fossa 70%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

WHO grading

A

1: low proliferative potential
2: infiltrative but low proliferative activity
3: malignant w/ nuclear atypia
4: malignant, necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Radiation Tx has this serious potential complication

A

patients are more prone to other types of cancers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Gliomas vs. Astrocytomas

A

same thing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Pilocytic astrocytoma

A

grade I astrocytoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Rosenthal fibers are found in which type of astrocytoma?

A

pilocytic astrocytoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Targeted BRAF Tx possible in this tumor

A

pilocytic astrocytoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How does one visualize BRAF hybridizations?

A

FISH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Is a BRAF-KIAA1549 fusion good or bad prognosis?

A

bad

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is Grade 1 astrocytoma?

A

pilocytic astrocytoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is Grade 2 astrocytoma?

A

diffuse astrocytoma

17
Q

Do diffuse astrocytomas typically become anaplastic?

A

yes

18
Q

Gemnistocytic subtype exists in this grade of astrocytoma

A

diffuse astrocytoma (2)

19
Q

What is Grade 3 astrocytoma?

A

anaplastic astrocytoma

20
Q

What is the GFAP protein?

A

glial fibrillary acidic protein

21
Q

What is the function of GFAP?

A

principle intermediate filament in astrocytes

22
Q

What is the pathological utility of GFAP?

A

one can stain for GFAP to stage

23
Q

GFAP is found in which stage of astrocytoma?

A

anaplastic astrocytoma (3)

24
Q

Grade 4 astrocytoma

A

glioblastoma multiforme

25
Q

What is a glioblastoma that crosses the midline called

A

butterfly

26
Q

What is the dead giveaway for glioblastoma?

A

necrosis

27
Q

Tumor that typically presents w/ seizures

A

oligodendrocytoma

28
Q

Which type of tumor are rosettes typically found?

A

ependymoma

29
Q

What are rosettes?

A

cells forming in a ring with fibrillary fibers in the middle that they secreted

30
Q

What is the dead giveaway for ependymomas?

A

rosettes

31
Q

Where do you find Pulmor-Wright rosettes?

A

medulloblastomas

32
Q

Where are medulloblastomas usually found?

A

posterior fossa of children

33
Q

This type of tumor may result in hearing loss

A

Schwannoma

34
Q

What is pseudopalisading necrosis?

A

palisading: perpendicular

looks like cells are running away from necrosis to get a fresh blood supply

Neuro Block 5-RG (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions