Sedatives-Hypnotics Flashcards
What should you assess before giving a sedative or hypnotic?
Vitals Sleep pattern Environmental control- temp, lights, noise Caffeinated products Respiratory status
What is the action of Barbiturates?
Reduce nerve impulses traveling to the cerebral cortex
Suppress REM and stages 3 & 4
When are Barbiturates used?
Sedative-hypnotics
Anticonvulsants
What are the side effects of Barbiturates as sedative-hypnotics?
CNS depression, hangover effect, hypotension, respiratory distress, dependence, rebound phenomenon, tolerance
What is an interaction that Barbiturates have?
Enzyme inducers- Warfarin
What is the action of Benzodiazepines?
Binds to GABA receptors
When are Benzodiazepines used?
Sedative-hypnotic, anti anxiety, anticonvulsants
What are the side effect of Benzodiazepines?
Hypotension, respiratory depression, hangover effect, retrograde amnesia, dependence, tolerance
What is an interaction that Benzodiazepines have?
Alcohol and other CNS depressants- additive effect
What enhances the metabolism of Benzodiazepines?
Smoking
What are Benzodiazepines contraindicated in?
Drug allergy
Severe respiratory disorders
Pregnancy
Decreased Level of consciousness
What do Benzodiazepines have a decreased effect with?
CNS stimulants- alcohol, meth
Barbiturates
What are some nursing considerations of Benzodiazepines?
Sleep apnea- makes worse Cardiac and respiratory function Mental status Use of alcohol or CNS depressants Liver, renal, CBC labs
Should Benzodiazepines be used for long or short term use?
Short term use
What is the action of NONbarbiturates or NONbenzodiazepines?
Bind to type 1 GABA receptors in the CNS