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Pharmacology > Antiepileptics > Flashcards

Antiepileptics Flashcards

1
Q

What are Barbiturate anti epileptics used for?

A

Partial and tonic-clonic seizures

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2
Q

What is the action of Barbiturate anti epileptics?

A

Depress sensory cortex, motor function, and cerebellar function

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3
Q

What are the side effects of Barbiturate anti epileptics?

A

Sedation, drowsiness, lethargy, Steven-Johnson Syndrome, excitement, nausea, teratogenic

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4
Q

What are Hydantoins used for?

A

Tonic-clonic and partial seizures

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5
Q

What is the action of Hydantoins?

A

Reduce spontaneous electrical impulses by blocking sodium

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6
Q

What are the side effects of Hydantoins?

A

Lethargy, abnormal movements, ataxia, gingival hyperplasia, teratogenic

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7
Q

What are Iminostilbenes used for?

A

Conjunction with other anticonvulsants to control partial seizures

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8
Q

What is the action of Iminostilbenes?

A

Decrease synaptic transmission

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9
Q

What are the side effects of Iminostilbenes?

A

Vertigo, visual disturbances, bone marrow suppression, thrombocytopenia, teratogenic

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10
Q

What should patients avoid when taking Iminostilbenes?

A

Grapefruit juice

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11
Q

What are Valproates used for?

A

Conjunction with other anticonvulsants to control simple and complex partial seizures

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12
Q

What is the action of Valproates?

A

Increases GABA

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13
Q

What are the side effects of Valproates?

A

Suicidal thoughts, sedation, confusion, hepatotoxicity, pancreatitis, teratogenic

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14
Q

What are Succinimides used for?

A

Absence seizures

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15
Q

What is the action of Succinimides?

A

Unknown

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16
Q

What are the side effects of Succinimides?

A

Sedation, drowsiness, dizziness, night terrors, aggression, leukopenia

17
Q

What are Benzodiazepines used for?

A

Status epileptics-first line

18
Q

What is the action of Benzodiazepines?

A

Binds GABA receptors in the CNS

19
Q

What are the side effects of Benzodiazepines?

A

Sedation, headache, dizziness, hypotension, respiratory distress, dependence, blood dyscrasias, hepatotoxicity

20
Q

What should we teach our patients about anti epileptic drugs?

A 
Take at same time, each day
Take with meals
Alternate form of oral hormonal contraception
Do not drive until 3 months seizure free
Long-term therapy

Pharmacology (19 decks)

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