Anti-emetics Flashcards
What are 5-HT3 Antagonists used for?
Nausea and vomiting with chemotherapy and surgery
What is the action of 5-HT3 Antagonists?
Block serotonin
What are the side effects of 5-HT3 Antagonists?
Diarrhea, constipation, headache, dizziness, muscle aches, fatigue
What is 5-HT3 Antagonists more effective with?
Dexamethasone
What are Phenothiazines used for?
Nausea and vomiting with surgery, opioids, motion sickness
What is the action of Phenothiazines?
Block dopamine
What are the side effects of Phenothiazines?
Sedation, cognitive impairment, EPS reactions, hypotension, dry mouth, urinary retention, constipation
What are corticosteroids used for?
Nausea and vomiting with chemotherapy
What is the action of corticosteroids?
Unknown
What are antihistamines used for?
Motion sickness and pregnancy
What is the action of antihistamines?
Blocks acetylcholine and histamine
What are the side effects of antihistamines?
Sedation, blurred vision, constipation, urinary retention, dry mouth
What are anticholinergics used for?
Motion sickness
What is the action of anticholinergics?
Blocks acetylcholine
What are the side effects of anticholinergics?
Dry mouth, high and dry effects
What type of medication is an anticholinergic anti-emetic?
Transdermal Patch
What are Benzodiazapines used for?
Decrease nervousness related to nausea and vomiting- cancer patients
What is the action of Benzodiazapines?
Produce relaxation and inhibit vomit center in brain
What are Prokinetics used for?
Gastric retention with food and fluids
What is the action of Prokinetics?
Increase GI motility
What are the side effects of Prokinetics?
Sedation, EPS reactions, restlessness
What is contraindicated with the use of Prokinetics?
Parkinson’s disease