Sedatives And Hypnotics 1 Flashcards
Define sedative
Define hypnotic
Define anxiolytic
Sedatives and hypnotics at very low dose will be what
Anxiolytic
Explain the sedative hypnotic drug dose dependent depression of the CNS
What are the two general classes of neurotransmitters
Biogenic amines
Amino acids
Examples of biogenic amines
Examples of amino acids
Is acetylcholine a biogenic amine or amino acid
What are the 2 kinds of post synaptic receptors
Ionitropic / ligand gated ion channels
Metabotropic/ G-protein coupled
What are the neurotransmitters in ligand gated ion channels
What are the neurotransmitters for G protein coupled
What are the classification of sedative hypnotics
What is the major inhibitory neurotransmitter
GABA
How do benzodiazepines work
How do barbiturates work
Can barbiturates and benzodiazepines be given together
What have the most powerful effect on the CNS that the other sedatives
Barbiturates
What effect does barbiturates have in different doses
Low dose - calming effect
Moderate dose - drunken euphoric state (like alcohol)
High dose - sedation and sleep occur
Very high dose - surgical, anesthesia
Barbiturates were popular in the treatment of what
Why are barbiturates rarely used
Explain benzodiazepines
What’s a similarity between benzodiazepines and barbiturates
Anticonvulsant effects
What is the use of benzodiazepines
