Anticoagulant Agents Flashcards
Define a thrombus
What are the 3 stages of hemostasis
How is blood clot formed
Is blood clot normal
What are the 2 main pathways for blood clot formation
What are the most important factors in blood clotting
Factor 10, 2 and 1
Compare between intrinsic and extrinsic pathway
What are the 3 types of anti clotting agents
Anticoagulants
Thrombolytics or antithrombotic or fibrinolytic agents
Anti-platelet
What are anticoagulants
What are Thrombolytics or antithrombotic or fibrinolytic agents
What are anti-platelet agents
Give example of anticoagulant therapy
Explain clopidogrel
Clopidogrel is prescribed for what
Explain how clopidogrel works
Clopidogrel
What is the mechanism of action of coumarins (warfarin)
Explain the SAR of coumarins
Explain heparin
Explain the mechanism of heparin
What are the types of heparin
Compare between unfractionated heparin and low molecular weight heparin
Explain the anticoagulant action of heparin
What is fondaparinux
What is rivaroxaban
Why is heparin not given IM
Because muscle has a lot of blood vessels so it will cause bleeding continuously
What is the antidote for heparin and warfarin
Heparin - protamine
Warfarin - potassium injection
What are thrombolytics
Give example of thrombolytic drug
Streptokinase
What is the mechanism of thrombolytics