Anticoagulant Agents Flashcards

1
Q

Define a thrombus

A
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2
Q

What are the 3 stages of hemostasis

A
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3
Q

How is blood clot formed

A
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4
Q

Is blood clot normal

A
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5
Q

What are the 2 main pathways for blood clot formation

A
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6
Q

What are the most important factors in blood clotting

A

Factor 10, 2 and 1

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7
Q

Compare between intrinsic and extrinsic pathway

A
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8
Q

What are the 3 types of anti clotting agents

A

Anticoagulants
Thrombolytics or antithrombotic or fibrinolytic agents
Anti-platelet

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9
Q

What are anticoagulants

A
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10
Q

What are Thrombolytics or antithrombotic or fibrinolytic agents

A
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11
Q

What are anti-platelet agents

A
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12
Q
A
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13
Q
A
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14
Q

Give example of anticoagulant therapy

A
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15
Q

Explain clopidogrel

A
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16
Q

Clopidogrel is prescribed for what

17
Q

Explain how clopidogrel works

18
Q
A

Clopidogrel

19
Q

What is the mechanism of action of coumarins (warfarin)

20
Q

Explain the SAR of coumarins

21
Q

Explain heparin

22
Q

Explain the mechanism of heparin

23
Q

What are the types of heparin

24
Q

Compare between unfractionated heparin and low molecular weight heparin

25
Q

Explain the anticoagulant action of heparin

26
Q

What is fondaparinux

27
Q

What is rivaroxaban

28
Q

Why is heparin not given IM

A

Because muscle has a lot of blood vessels so it will cause bleeding continuously

29
Q

What is the antidote for heparin and warfarin

A

Heparin - protamine
Warfarin - potassium injection

30
Q

What are thrombolytics

31
Q

Give example of thrombolytic drug

A

Streptokinase

32
Q

What is the mechanism of thrombolytics