Anticoagulant Agents Flashcards

1
Q

Define a thrombus

A
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2
Q

What are the 3 stages of hemostasis

A
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3
Q

How is blood clot formed

A
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4
Q

Is blood clot normal

A
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5
Q

What are the 2 main pathways for blood clot formation

A
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6
Q

What are the most important factors in blood clotting

A

Factor 10, 2 and 1

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7
Q

Compare between intrinsic and extrinsic pathway

A
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8
Q

What are the 3 types of anti clotting agents

A

Anticoagulants
Thrombolytics or antithrombotic or fibrinolytic agents
Anti-platelet

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9
Q

What are anticoagulants

A
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10
Q

What are Thrombolytics or antithrombotic or fibrinolytic agents

A
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11
Q

What are anti-platelet agents

A
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12
Q
A
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13
Q
A
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14
Q

Give example of anticoagulant therapy

A
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15
Q

Explain clopidogrel

A
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16
Q

Clopidogrel is prescribed for what

17
Q

Explain how clopidogrel works

18
Q
A

Clopidogrel

19
Q

What is the mechanism of action of coumarins (warfarin)

20
Q

Explain the SAR of coumarins

21
Q

Explain heparin

22
Q

Explain the mechanism of heparin

23
Q

What are the types of heparin

24
Q

Compare between unfractionated heparin and low molecular weight heparin

25
Explain the anticoagulant action of heparin
26
What is fondaparinux
27
What is rivaroxaban
28
Why is heparin not given IM
Because muscle has a lot of blood vessels so it will cause bleeding continuously
29
What is the antidote for heparin and warfarin
Heparin - protamine Warfarin - potassium injection
30
What are thrombolytics
31
Give example of thrombolytic drug
Streptokinase
32
What is the mechanism of thrombolytics