Antipsychotic Drugs

Question 1

What are the symptoms of schizophrenia

Answer 1

Question 2

Explain schizophrenia etiology

Answer 2

Question 3

What are the 1st generation drugs for schizophrenia

Answer 3

Question 4

What are the 2nd generation drugs for schizophrenia

Answer 4

Question 5

Answer 5

Question 6

What is the effect of D2 antagonist on the nigrostriatal pathway

Answer 6

Question 7

What is the effect of D2 antagonist on the mesocortical pathway

Answer 7

Question 8

What is the effect of D2 antagonist on the mesolimbic pathway

Answer 8

Question 9

What is the effect of D2 antagonist on the tuberoinfundibular pathway

Answer 9

Question 10

What are the adverse effects of typical neuroleptics

Answer 10

Question 11

List the antipsychotic classes

Answer 11

Question 12

Explain phenothiazines

Answer 12

Question 13

The SAR of phenothiazines includes what

Answer 13

N10 substitution
Modification of amino group side chain
Modification of X
Modification of tricyclic structure

Question 14

Explain the N10 substitution as SAR of phenothiazine

Answer 14

Question 15

Explain the modification of amino group side chain as SAR of phenothiazine

Answer 15

Question 16

Explain the modification of X as SAR of phenothiazine

Answer 16

Question 17

Explain the modification of tricyclic structure as SAR of phenothiazine

Answer 17

Question 18

Explain long acting neuroleptics and give example

Answer 18

Question 19

Explain butyrophenones

Answer 19

Question 20

Explain atypical antipsychotics

Answer 20

Question 21

Give example of atypical antipsychotics

Answer 21

Question 22

Explain benzamides

Answer 22

Question 23

Explain benzazepine

Answer 23

Question 24

Explain olanzapine

Answer 24

Question 25

Explain quetiapine

Answer 25