Antihypertensive Agents ( Sympatholytics) Flashcards
What type of sympatholytics used as antihypertensive drugs
What is the main action of sympatholytics
What are the subtypes of sympatholytics antihypertensive
what are the centrally acting agents
a2 selective agonists
What is the indication for alpha2 selective agonists
Explain an example of alpha2 agonist for hypertension
Explain the side effects of clonidine
What is methyldopa
How does methyldopa act as antihypertensive
Give example of ganglion in blocker
Trimethapan
What is the indication of trimethapan
Severe hypertension
What’s the mechanism of trimethapan
What is the toxicity of trimethapan
Does trimethapan have CNS effects
It has a positive charge so cannot cross BBB so no CNS effects
Trimethapan is only used when
What is reserpine
How does reserpine work
Explain the toxicity of reserpine
How does guanethidine work
Explain the side effects of guanethidine
Adrenoceptor blockers include what
What is the indication for adrenoceptor blockers
Explain the toxicity of adrenoceptor blockers
Explain an example of non selective alpha beta antagonist
Give example of B1 receptor antagonist
What is B1 receptor antagonists used for
Give example of alpha 1 receptor antagonists
What is the action of alpha 1 receptor antagonists
What is a side effect of alpha 1 receptor antagonists
Orthostatic hypotension