Antihypertensive Agents ( Sympatholytics) Flashcards by Лили Ауси

Q

What type of sympatholytics used as antihypertensive drugs

A

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Q

What is the main action of sympatholytics

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Q

What are the subtypes of sympatholytics antihypertensive

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Q

what are the centrally acting agents

A

a2 selective agonists

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Q

What is the indication for alpha2 selective agonists

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Q

Explain an example of alpha2 agonist for hypertension

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Q

Explain the side effects of clonidine

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Q

What is methyldopa

A

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Q

How does methyldopa act as antihypertensive

A

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Q

Give example of ganglion in blocker

A

Trimethapan

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Q

What is the indication of trimethapan

A

Severe hypertension

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Q

What’s the mechanism of trimethapan

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Q

What is the toxicity of trimethapan

A

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Q

Does trimethapan have CNS effects

A

It has a positive charge so cannot cross BBB so no CNS effects

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Q

Trimethapan is only used when

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Q

What is reserpine

A

Q

How does reserpine work

A

Q

Explain the toxicity of reserpine

A

Q

How does guanethidine work

A

Q

Explain the side effects of guanethidine

A

Q

Adrenoceptor blockers include what

A

Q

What is the indication for adrenoceptor blockers

A

Q

Explain the toxicity of adrenoceptor blockers

A

Q

Explain an example of non selective alpha beta antagonist

A

Give example of B1 receptor antagonist

What is B1 receptor antagonists used for

Give example of alpha 1 receptor antagonists

What is the action of alpha 1 receptor antagonists

What is a side effect of alpha 1 receptor antagonists

Orthostatic hypotension