Antihypertensive Agents ( Sympatholytics) Flashcards

1
Q

What type of sympatholytics used as antihypertensive drugs

A
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2
Q

What is the main action of sympatholytics

A
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3
Q

What are the subtypes of sympatholytics antihypertensive

A
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4
Q

what are the centrally acting agents

A

a2 selective agonists

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5
Q

What is the indication for alpha2 selective agonists

A
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6
Q

Explain an example of alpha2 agonist for hypertension

A
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7
Q

Explain the side effects of clonidine

A
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8
Q

What is methyldopa

A
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9
Q

How does methyldopa act as antihypertensive

A
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10
Q

Give example of ganglion in blocker

A

Trimethapan

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11
Q

What is the indication of trimethapan

A

Severe hypertension

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12
Q

What’s the mechanism of trimethapan

A
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13
Q

What is the toxicity of trimethapan

A
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14
Q

Does trimethapan have CNS effects

A

It has a positive charge so cannot cross BBB so no CNS effects

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15
Q

Trimethapan is only used when

A
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16
Q

What is reserpine

17
Q

How does reserpine work

18
Q

Explain the toxicity of reserpine

19
Q

How does guanethidine work

20
Q

Explain the side effects of guanethidine

21
Q

Adrenoceptor blockers include what

22
Q

What is the indication for adrenoceptor blockers

23
Q

Explain the toxicity of adrenoceptor blockers

24
Q

Explain an example of non selective alpha beta antagonist

25
Q

Give example of B1 receptor antagonist

26
Q

What is B1 receptor antagonists used for

27
Q

Give example of alpha 1 receptor antagonists

28
Q

What is the action of alpha 1 receptor antagonists

29
Q

What is a side effect of alpha 1 receptor antagonists

A

Orthostatic hypotension