Screening tools Flashcards

1
Q

Goal of PCa screening?

A

early detection

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2
Q

Digital rectal examination - DRE

A
  • specificty
  • low cost
  • safe + ease
  • only moderate sensitivity
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3
Q

what is prostate-specific antigen - PSA a marker for?

member human kallikrein gene - serine protease - produced in coloumnar secretroy cells of prostate

A
  • detected early PCa
  • predict outcome localized disease
  • monitor disease-free status
  • monitor response to treatment of advance-stage disease
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4
Q

Advantages of PSA

A
  • Non-invasive
    -ease
    l- low specificity - elevated in men who are smokers , cases urinary retetnion, acute prostatitis, BPH
    = not all men with PCa have high PSA
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5
Q

Is 5-alpha reductase inhibitors recommended for PCa ?

A

No, as it can cause higher grade tumours

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