Screening tools Flashcards
1
Q
Goal of PCa screening?
A
early detection
2
Q
Digital rectal examination - DRE
A
- specificty
- low cost
- safe + ease
- only moderate sensitivity
3
Q
what is prostate-specific antigen - PSA a marker for?
member human kallikrein gene - serine protease - produced in coloumnar secretroy cells of prostate
A
- detected early PCa
- predict outcome localized disease
- monitor disease-free status
- monitor response to treatment of advance-stage disease
4
Q
Advantages of PSA
A
- Non-invasive
-ease
l- low specificity - elevated in men who are smokers , cases urinary retetnion, acute prostatitis, BPH
= not all men with PCa have high PSA
5
Q
Is 5-alpha reductase inhibitors recommended for PCa ?
A
No, as it can cause higher grade tumours